This issue of Surgical Oncology Clinics of North America focuses on Biliary Tract and Primary Liver Tumors and is edited by Dr. T. Clark Gamblin. Articles will include: Biliary Tract and Primary Liver Tumors; Biliary Tract and Primary Liver Tumors: Who, What and Why?; Imaging Updates for Biliary Tract or Primary Liver Tumors; Endoscopic and Percutaneous Approaches to Treat of Biliary Tract and Primary Liver Tumors: Controversies and Advances; Intrahepatic Cholangiocarcinoma: Strategies and Options; Surgical Considerations of Hilar Cholangiocarcinoma; Gall Bladder Cancer: Managing the Incidental Diagnosis; Approaches and Outcomes to Distal Cholangiocarcinoma; Evolving Surgical Options of Hepatocellular Carcinoma; Staging of Biliary and Primary Liver Tumors: Current Reccomendations and Workup; Systemic and Targeted Therapy for Biliary Tract Tumors and Primary Liver Tumors; Regional Chemotherapy for Biliary Tract and Primary Liver Cancer; Role of Radioembolization for Biliary Tract and Primary Liver Cancer; Inoperable Biliary Tract and Primary Liver Tumors: Palliative Treatment Options; Expanding the Surgical Pool for Hepatic Resection to Treat Biliary and Primary Liver Tumors; and more!

This issue of Neurosurgery Clinics of North America is devoted to "Advances in Neuromodulation." Editors Won Kim, MD, Antonio De Salles, MD, and Nader Pouratian, MD have assembled the top experts to review topics such as: peripheral nerve stimulation; spinal cord stimulation for gait reanimation and vascular pathology; deep brain stimulation for Tourettes, OCD, depression, Parkinson’s disease, eating disorders, dystonia, and headache; and techniques for image-guided deep brain stimulation, advanced imaging for targeting, and closed loop neuromodulation.

In this issue of Neurosurgery Clinics, guest editors Drs. Joshua M. Rosenow and Julie G. Pilitsis bring their considerable expertise to the topic of Pain Management. Because pain management often benefits from a multidisciplinary approach, this issue addresses how pain can be assessed and managed with and without medication (e.g., acupuncture, chiropractic medicine, mindfulness meditation) and procedures. - Contains 15 relevant, practice-oriented topics including the multidisciplinary team in pain management; healthcare disparity in pain; nonopioid postoperative pain management; holistic therapy: what works and what does not; machine learning and pain outcomes; and more. - Provides in-depth clinical reviews on pain management, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Medications for epilepsy are mainstays in controlling epileptic seizures. But surgical procedures are another dimension in treatment. Included in this issue will be articles such as: Laser ablation for hypothalamic hamartomas and other epileptic lesions, radiosurgery for epilepsy, minimally invasive neurosurgery using focused MRI guidance, Selective amygdalohippocampectomy, and many more!

This issue provides a glimpse into how pain can be assessed and managed by several medical disciplines and approaches. It covers classical and conventional techniques as well as innovative techniques.

In this issue of Neurosurgery Clinics, Drs. Chang and Barbaro provide a thorough look at epilepsy, with sections focusing on devices in epilepsy surgery, open loop systems, closed loop systems, and non-stimulation. Topics in this issue include history and overview of stimulation for epilepsy, trigeminal nerve stimulation, anterior thalamus DBS, hippocampal stimulation, neuropace RNS, seizure detection/prediction algorithms, cooling, seizure prediction and its applications, stimulation paradigms, and experimental stimulation.

This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.