The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

To this day, the perception persists that China was a civilization defeated by imperialist Britain's most desirable trade commodity, opium—a drug that turned the Chinese into cadaverous addicts in the iron grip of dependence. Britain, in an effort to reverse the damage caused by opium addiction, launched its own version of the "war on drugs," which lasted roughly sixty years, from 1880 to World War II and the beginning of Chinese communism. But, as Narcotic Culture brilliantly shows, the real scandal in Chinese history was not the expansion of the drug trade by Britain in the early nineteenth century, but rather the failure of the British to grasp the consequences of prohibition. In a stunning historical reversal, Frank Dikötter, Lars Laamann, and Zhou Xun tell this different story of the relationship between opium and the Chinese. They reveal that opium actually had few harmful effects on either health or longevity; in fact, it was prepared and appreciated in highly complex rituals with inbuilt constraints preventing excessive use. Opium was even used as a medicinal panacea in China before the availability of aspirin and penicillin. But as a result of the British effort to eradicate opium, the Chinese turned from the relatively benign use of that drug to heroin, morphine, cocaine, and countless other psychoactive substances. Narcotic Culture provides abundant evidence that the transition from a tolerated opium culture to a system of prohibition produced a "cure" that was far worse than the disease. Delving into a history of drugs and their abuses, Narcotic Culture is part revisionist history of imperial and twentieth-century Britain and part sobering portrait of the dangers of prohibition.

The Politics of Narcotic Drugs brings together leading experts on the drugs trade to provide an accessible yet detailed analysis of the multiple challenges that the contemporary trade in narcotic drugs and its prohibition pose, from the local to the international community. Through the use of country and regional case studies that include Afghanistan, Mexico, Colombia and the Middle East, the drivers of the drugs trade and the security and development dilemmas created by the prohibition of narcotic substances are explored. Contributions that assess the international drug control regime, British anti-drug enforcement organizations, 'narcoterrorism' and options for drug policy reform engage readers in current debates and the narrative frameworks that shape discussion of the drugs issue. The book is an invaluable guide to the dynamic and far-reaching issue of narcotic drugs and the impact of their prohibition on our countries and communities. The chapters are followed by an A-Z glossary of key terms, issues and organizations, and a section of maps and statistics.

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

A clear-eyed look at the instrumental role drugs have played in our cultural, social, and spiritual development. • First American publication of the surprising European bestseller. • Examines everything from the ancient use of ergot and datura to the modern phenomenon of "designer" drugs such as Ecstasy and crack cocaine. From remotest antiquity to the present era of designer drugs and interdiction, drugs have played a prominent role in the cultural, spiritual, and social development of civilizations. Antonio Escohotado demonstrates how the history of drugs illuminates the history of humanity as he explores the long relationship between mankind and mind-altering substances. Hemp, for example, has been used in India since time immemorial to stimulate mental agility and sexual prowess. Aristotle's disciple Theophrastus testifies to the use of datura by the ancient Greeks and further evidence links the rites at Eleusis to the ingestion of a hallucinogen. Similar examples can be found in cultures as diverse as the Celts, the ancient Egyptians, the Aztecs, and other indigenous peoples around the world. Professor Escohotado also looks at the present-day differences that exist between the more drug-tolerant societies like Holland and Switzerland and countries advocating complete repression of these substances. The author provides a comprehensive analysis of the enormous social costs of the drug war that is coming under increasing fire from all levels of society. Professor Escohotado's work demonstrates that drugs have always existed and been used by societies throughout the world and the contribution they have made to humanity's development has been enormous. The choice we face today is to teach people how to use them correctly or to continue to indiscriminately demonize them. "Just say no," the author says, is not an option. Just say "know" is. Antonio Escohotado is a professor of philosophy and social science methodology at the National University of Distance Education in Madrid, Spain. He travels widely, offering lectures and seminars on the subject of drugs and history.

This book uncovers the mysterious aura surrounding drugs o provide answers to questions like what are they, why do they entrap a person in their clutches and how we can stay free of their mind altering effects.

A collection of essays exploring the complex history of drugs and narcotics throughout historyfrom ancient Greece to the present dayshows that such substances were sought originally as healing agents, both within and without the medical profession. However, the mood- and mind-altering characteristics of some have led to the widespread abuse and legal controls we see today.