Disclosure statement: Topic Editor Prof. Silvia Salinas Blemker is a Co-founder and Vice President of Springbok, Inc. Charlottesville, VA. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

The term "neuromechanics" defines an integrative approach that combines the neuromuscular control and the biomechanical aspects of physical behavior in humans and animals. Crucial to this approach is a detailed description and modeling of the interaction between the nervous system and the controlled biomechanical plant. Only then do we have the broader context within which to understand evolution, movement mechanics, neural control, energetics, disability and rehabilitation. In addition to enabling new basic science directions, understanding the interrelations between movement neural and mechanical function should also be leveraged for the development of personalized wearable technologies to augment or restore the motor capabilities of healthy or impaired individuals. Similarly, this understanding will empower us to revisit current approaches to the design and control of robotic and humanoid systems to produce truly versatile human-like physical behavior and adaptation in real-world environments. This Research Topic is therefore poised at an opportune moment to promote understanding of apparently disparate topics into a coherent focus.

Bioinspired Legged Locomotion: Models, Concepts, Control and Applications explores the universe of legged robots, bringing in perspectives from engineering, biology, motion science, and medicine to provide a comprehensive overview of the field. With comprehensive coverage, each chapter brings outlines, and an abstract, introduction, new developments, and a summary. Beginning with bio-inspired locomotion concepts, the book's editors present a thorough review of current literature that is followed by a more detailed view of bouncing, swinging, and balancing, the three fundamental sub functions of locomotion. This part is closed with a presentation of conceptual models for locomotion. Next, the book explores bio-inspired body design, discussing the concepts of motion control, stability, efficiency, and robustness. The morphology of legged robots follows this discussion, including biped and quadruped designs. Finally, a section on high-level control and applications discusses neuromuscular models, closing the book with examples of applications and discussions of performance, efficiency, and robustness. At the end, the editors share their perspective on the future directions of each area, presenting state-of-the-art knowledge on the subject using a structured and consistent approach that will help researchers in both academia and industry formulate a better understanding of bioinspired legged robotic locomotion and quickly apply the concepts in research or products. - Presents state-of-the-art control approaches with biological relevance - Provides a thorough understanding of the principles of organization of biological locomotion - Teaches the organization of complex systems based on low-dimensional motion concepts/control - Acts as a guideline reference for future robots/assistive devices with legged architecture - Includes a selective bibliography on the most relevant published articles

Vascular dementia is one of the most common forms of mental deterioration for the elderly, second only to Alzheimer's disease. It should not be defined as a single disease, but rather as a group of syndromes that relate to different vascular mechanisms. This is one of the first books to be solely dedicated to the specific class of vascular dementia known as subcortical vascular dementia. The strict focus of the chapters give an depth review that will clarify many different aspects and give an unprecedented amount of detail about this clinical problem. Considering that vascular dementia can be prevented with early diagnosis, the research presented in this book will be important for both students and specialists of this important field.

This book offers a comprehensive set of principles that lead to ideal outcomes following treatment for Head and Neck Cancers, especially in those patients who need major reconstructive procedures. It goes beyond the scope of basic Head and Neck Cancer textbooks, or of reconstructive surgery texts, in that the essential focus is on optimal outcomes beyond fundamental evaluation and management. The book addresses a range of essential aspects: the chapters on Functional and Aesthetic considerations underscore crucial basics that should be understood by all surgeons, while other chapters relevant to all members of the Head and Neck team address Imaging, Robotics, Radiation Morbidities, Prosthetics and Quality of Life. Throughout the book, particular attention is given to high-quality photographs, flow diagrams and tables wherever possible, combined with crisp writing to achieve effective communication. The book is unique in the completeness of its approach: from the time of initial presentation, to the time patients resume their normal lives. Although written primarily for surgeons, its value extends to all members of the multi-disciplinary team managing Head and Neck Cancer patients today.

This book reports on the latest technological and clinical advances in the field of neurorehabilitation. It is, however, much more than a conventional survey of the state-of-the-art in neurorehabilitation technologies and therapies. It was formed on the basis of a week of lively discussions between curious PhD students and leading research experts during the summer school on neurorehabilitation (SSNR2012), September 16-21 in Nuévalos, Zaragoza (Spain). Its unconventional format makes it a perfect guide for all PhD students, researchers and professionals interested in gaining a multidisciplinary perspective on current and future neurorehabilitation scenarios. The book covers various aspects of neurorehabilitation research and practice, organized into different parts. The first part discusses a selection of common impairments affecting brain function, such as stroke, cerebral palsy and Parkinson’s disease; the second deals with both spinal cord and brain plasticity. The third part covers the most recent rehabilitation and diagnostics technologies, including robotics, neuroprostheses, brain-machine interfaces and electromyography systems. Practical examples and case studies related to the application of some of the latest techniques in realistic clinical scenarios are covered in the fourth part.