This applied, self-contained text provides detailed coverage of the practical aspects of multivariate statistical process control (MVSPC)based on the application of Hotelling's T2 statistic. MVSPC is the application of multivariate statistical techniques to improve the quality and productivity of an industrial process. The authors, leading researchers in this area who have developed major software for this type of charting procedure, provide valuable insight into the T2 statistic. Intentionally including only a minimal amount of theory, they lead readers through the construction and monitoring phases of the T2 control statistic using numerous industrial examples taken primarily from the chemical and power industries. These examples are applied to the construction of historical data sets to serve as a point of reference for the control procedure and are also applied to the monitoring phase, where emphasis is placed on signal location and interpretation in terms of the process variables.

Given their key position in the process control industry, process monitoring techniques have been extensively investigated by industrial practitioners and academic control researchers. Multivariate statistical process control (MSPC) is one of the most popular data-based methods for process monitoring and is widely used in various industrial areas. Effective routines for process monitoring can help operators run industrial processes efficiently at the same time as maintaining high product quality. Multivariate Statistical Process Control reviews the developments and improvements that have been made to MSPC over the last decade, and goes on to propose a series of new MSPC-based approaches for complex process monitoring. These new methods are demonstrated in several case studies from the chemical, biological, and semiconductor industrial areas. Control and process engineers, and academic researchers in the process monitoring, process control and fault detection and isolation (FDI) disciplines will be interested in this book. It can also be used to provide supplementary material and industrial insight for graduate and advanced undergraduate students, and graduate engineers. Advances in Industrial Control aims to report and encourage the transfer of technology in control engineering. The rapid development of control technology has an impact on all areas of the control discipline. The series offers an opportunity for researchers to present an extended exposition of new work in all aspects of industrial control.

Provides a theoretical foundation as well as practical tools for the analysis of multivariate data, using case studies and MINITAB computer macros to illustrate basic and advanced quality control methods. This work offers an approach to quality control that relies on statistical tolerance regions, and discusses computer graphic analysis highlightin

​​​​​The intensive use of automatic data acquisition system and the use of cloud computing for process monitoring have led to an increased occurrence of industrial processes that utilize statistical process control and capability analysis. These analyses are performed almost exclusively with multivariate methodologies. The aim of this Brief is to present the most important MSQC techniques developed in R language. The book is divided into two parts. The first part contains the basic R elements, an introduction to statistical procedures, and the main aspects related to Statistical Quality Control (SQC). The second part covers the construction of multivariate control charts, the calculation of Multivariate Capability Indices.

Multivariate Analysis in the Pharmaceutical Industry provides industry practitioners with guidance on multivariate data methods and their applications over the lifecycle of a pharmaceutical product, from process development, to routine manufacturing, focusing on the challenges specific to each step. It includes an overview of regulatory guidance specific to the use of these methods, along with perspectives on the applications of these methods that allow for testing, monitoring and controlling products and processes. The book seeks to put multivariate analysis into a pharmaceutical context for the benefit of pharmaceutical practitioners, potential practitioners, managers and regulators. Users will find a resources that addresses an unmet need on how pharmaceutical industry professionals can extract value from data that is routinely collected on products and processes, especially as these techniques become more widely used, and ultimately, expected by regulators. - Targets pharmaceutical industry practitioners and regulatory staff by addressing industry specific challenges - Includes case studies from different pharmaceutical companies and across product lifecycle of to introduce readers to the breadth of applications - Contains information on the current regulatory framework which will shape how multivariate analysis (MVA) is used in years to come

A major tool for quality control and management, statistical process control (SPC) monitors sequential processes, such as production lines and Internet traffic, to ensure that they work stably and satisfactorily. Along with covering traditional methods, Introduction to Statistical Process Control describes many recent SPC methods that improve upon

The normal or bell curve distribution is far more common in statistics textbooks than it is in real factories, where processes follow non-normal and often highly skewed distributions. Statistical Process Control for Real-World Applications shows how to handle non-normal applications scientifically and explain the methodology to suppliers and custom