By sharing the story of her genes, Mom is empowering her children to learn about their family's health history. Mom's Genes will help you start a conversation with your young children about genetics and how it plays a role in their own health. With age appropriate content, rhythm verse and vivid illustrations, Mom's Genes can help you teach your children the importance of being proactive about their health and wellness at a young age. Mom's Genes also includes interactive elements such as a search and find game, a glossary to emphasize key concepts, and a simple family tree for young children to use to explore their own family history. Mom's Genes was written by Shannon Pulaski. Just four months after giving birth to her twin daughters, Shannon discovered that she inherited a genetic mutation that greatly increased her risk of developing cancer in her lifetime. Understanding what was at risk, she made the decision to be proactive about her health and take affirmative action to reduce her risk of hereditary cancer. As a mother, Shannon Pulaski has felt compelled to share her family's health history with her children so that they can understand risk, live proactively, and become educated patients. She created Mom's Genes to help families get a conversation started about their own family's health history. To learn more, visit www.proactivegenes.com

2019 PEN/E.O. Wilson Literary Science Writing Award Finalist "Science book of the year"—The Guardian One of New York Times 100 Notable Books for 2018 One of Publishers Weekly's Top Ten Books of 2018 One of Kirkus's Best Books of 2018 One of Mental Floss's Best Books of 2018 One of Science Friday's Best Science Books of 2018 “Extraordinary”—New York Times Book Review "Magisterial"—The Atlantic "Engrossing"—Wired "Leading contender as the most outstanding nonfiction work of the year"—Minneapolis Star-Tribune Celebrated New York Times columnist and science writer Carl Zimmer presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities... But, Zimmer writes, “Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are—our appearance, our height, our penchants—in inconceivably subtle ways.” Heredity isn’t just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors—using a word that once referred to kingdoms and estates—but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer’s lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world’s best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

Cats are incredible creatures: they can eat practically anything and live almost anywhere. Tracing their rise from prehistory to the modern cat craze, Abigail Tucker presents an adventure through history, natural science, and pop culture. With keen reporting and lively wit, Tucker investigates the way house cats have used their relationship with humans to become one of the most powerful animals on the planet--

DISCOVER HOW LIFE REALLY WORKS - ON EARTH AND IN SPACE 'A wonderfully insightful sidelong look at Earthly biology' Richard Dawkins 'Crawls with curious facts' Sunday Times _________________________ We are unprepared for the greatest discovery of modern science. Scientists are confident that there is alien life across the universe yet we have not moved beyond our perception of 'aliens' as Hollywood stereotypes. The time has come to abandon our fixation on alien monsters and place our expectations on solid scientific footing. Using his own expert understanding of life on Earth and Darwin's theory of evolution - which applies throughout the universe - Cambridge zoologist Dr Arik Kershenbaum explains what alien life must be like. This is the story of how life really works, on Earth and in space. _________________________ 'An entertaining, eye-opening and, above all, a hopeful view of what - or who - might be out there in the cosmos' Philip Ball, author of Nature's Patterns 'A fascinating insight into the deepest of questions: what might an alien actually look like' Lewis Dartnell, author of Origins 'If you don't want to be surprised by extraterrestrial life, look no further than this lively overview of the laws of evolution that have produced life on earth' Frans de Waal, author of Mama's Last Hug

This unique and important guidebook is a single, comprehensive source of information and advice to help women (and some men) at high risk for breast and for ovarian cancer because of family history and genetic profile. One part memoir, three parts "how to" manual, Positive Results explains in a clear and steady manner the myths and realities of "the breast cancer genes." It lays out all the options in easy-to-follow, compassionate language. It will help women and men decide if they want to pursue genetic testing, guide them in interpreting their test results, and give them a sound basis for making the life-saving decisions required to manage their risks. Authors Joi Morris and Dr. Ora Karp Gordon cover all of the latest medical options, including genetic testing for breast cancer risk, breast cancer surveillance, assessing risk, mastectomy and breast reconstruction techniques, ovarian cancer surveillance, surgery, managing menopause, and cancer risks in men who carry mutations on BRCA genes. Along the way, Joi tells her personal story and that of other women and men who have made the gut-wrenching decisions required to survive in this world of astronomical risk. At the age of forty-two, Joi learned that she has a genetic mutation on a gene known as BRCA2. The test results meant that her risk of getting breast cancer could be as high as 84 percent by age seventy, and that her risk for ovarian cancer was also high. Compounding her risk was the fact that her mother had developed breast cancer in her forties. After much research and consultation, the result of which is this book, Joi made the difficult decision of undergoing prophylactic mastectomies. This straightforward and practical approach combined with the poignant personal experience of a woman at risk facing these challenging decisions will provide readers with the feeling that they have had the benefit of a long conversation with both a trusted physician and a friend who has just gone through the same uncertainties they are facing.

Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References

"Everyone knows how babies are made, but scientists are only just beginning to understand the making of a mother. Mom Genes reveals the hard science behind our tenderest maternal impulses, tackling questions such as whether a new mom's brain ever really bounces back, why mothers are destined to mimic their own moms (or not), and how maternal aggression makes females the world's most formidable creatures."--Publisher's description.