Modern Nucleophilic Aromatic Substitution
Title | Modern Nucleophilic Aromatic Substitution PDF eBook |
Author | Francois Terrier |
Publisher | John Wiley & Sons |
Pages | 488 |
Release | 2013-05-20 |
Genre | Science |
ISBN | 3527656162 |
This book provides a comprehensive overview of nucleophilic aromatic substitutions, focusing on the mechanistic and synthetic features that govern these reactions. The first chapter presents a detailed mechanistic analysis of the factors determining the feasibility of SNAr substitutions, providing decisive information to predict regioselectivity of many reactions and to define the conditions for concerted SNAr processes. Reflecting the key role played by these species as intermediates in most SNAr reactions, chapter 2 then discusses the chemistry of anionic sigma-complexes. Chapter 3 describes the concept of superelectrophilicity in SNAr substitutions, as it has recently emerged from the reactivity of strongly electron-deficient aromatic and heteroaromatic structures. The numerous synthetic applications are considered in depth in the chapters 4 and 5 that follow on intermolecular and intramolecular nucleophilic aromatic substitutions. Then, chapter 6 focuses on substitutions proceeding formally through displacement of a hydride ion, a hot topic in the field. The final chapter brings together concise yet comprehensive discussions surrounding SNAr photosubstitutions, radical substitutions, and ANRORC substitutions. Authored by a highly respected chemist who has contributed greatly to the field over the past two decades, this is a valuable information source for all organic chemists working in academia or the pharmaceutical and agrochemical industries.
Nucleophilic Aromatic Substitution of Hydrogen
Title | Nucleophilic Aromatic Substitution of Hydrogen PDF eBook |
Author | Oleg N. Chupakhin |
Publisher | Academic Press |
Pages | 378 |
Release | 2012-12-02 |
Genre | Science |
ISBN | 0323140599 |
Nucleophilic aromatic substitution in carbo- and heteroaromatic systems is a subject of considerable interest to chemists. This book uniquely addresses the systematic analysis of a vast range of nucleophilic substitutions of aromatic hydrogen. - Nucleophilic displacement of hydrogen (the S N/H reactions) in pi-deficient aromatics, such as nitroarenes, arene-metal complexes, and the like - Nucleophilic displacement of hydrogen in heterocyclic substrates such as pyridines, their aza and benzo analogs, pyrylium and thiapyrylium cations, and other heterocycles - Mechanisms for the S N/H reactions (S N/H(AE), vicarious nucleophilic substitutions, and radical S N/H substitutions
Nucleophilic Aromatic Substitution Reactions
Title | Nucleophilic Aromatic Substitution Reactions PDF eBook |
Author | Irianto Iguh Setiarahardjo |
Publisher | |
Pages | 148 |
Release | 1990 |
Genre | Amines |
ISBN |
Studies in nucleophilic aromatic substitution
Title | Studies in nucleophilic aromatic substitution PDF eBook |
Author | Bo Lamm |
Publisher | |
Pages | 19 |
Release | 1966 |
Genre | |
ISBN |
Studies in nucleophilic aromatic substitution
Title | Studies in nucleophilic aromatic substitution PDF eBook |
Author | |
Publisher | |
Pages | 19 |
Release | 1966 |
Genre | |
ISBN |
Organic Chemistry
Title | Organic Chemistry PDF eBook |
Author | Penny Chaloner |
Publisher | CRC Press |
Pages | 1272 |
Release | 2014-12-15 |
Genre | Medical |
ISBN | 1482206919 |
Offering a different, more engaging approach to teaching and learning, Organic Chemistry: A Mechanistic Approach classifies organic chemistry according to mechanism rather than by functional group. The book elicits an understanding of the material, by means of problem solving, instead of purely requiring memorization. The text enables a deep unders
Modern Physical Organic Chemistry
Title | Modern Physical Organic Chemistry PDF eBook |
Author | Eric V. Anslyn |
Publisher | University Science Books |
Pages | 1148 |
Release | 2006 |
Genre | Science |
ISBN | 9781891389313 |
In additionto covering thoroughly the core areas of physical organic chemistry -structure and mechanism - this book will escortthe practitioner of organic chemistry into a field that has been thoroughlyupdated.