With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

In one case after another, Charles L. Bosk reveals the process by which parents, physicians and other health professionals come to guide decisions about pregnancies. A story of both extraordinary drama and ordinary routine, this is a pioneering case study of authority and control in a pediatric hospital, showing how genetic counselors work with colleagues and with parents to be, and how they deal with their powerlessness to control life-and-death decisions that they must address.

Requesting, recruitment, and other ways of mobilizing others to act have garnered much interest in Conversation Analysis and Interactional Linguistics. This volume takes a holistic perspective on the practices that we use to get others to act either with us, or for us. It argues for a more explicit focus on ‘activity’ in unpacking the linguistic and embodied choices we make in designing mobilizing moves. Drawing on studies from a variety of different languages and settings, the collected studies in this volume illustrate how interactants design their turns not only for specific recipients, but also for a specific interactional situation. In doing so, speakers are able to mobilize others’ cooperation, contribution, or assistance in the most appropriate and economical ways. By focusing on ‘situation design’ across languages and settings, this volume provides new insights into the ways in which the ongoing activity, with its attendant participation structures, shapes the design, placement, and understanding of moves which mobilize others to act.

The author explores the changing rhetoric of pain medicine and how this rhetoric ultimately shapes the health-care community's understanding of what pain medicine is, how the medicine should be practiced and regulated, and how practitioner-patient relationships are best managed. -- Dust jacket.

In the months leading up to the 2016 presidential election, liberal outcry over ethnonationalist views promoted a vision of America as a nation of immigrants. Given the pervasiveness of this rhetoric, it can be easy to overlook the fact that the immigrant rights movement began in the US relatively recently. This book tells the story of its grassroots origins, through its meteoric rise to the national stage. Starting in the 1990s, the immigrant rights movement slowly cohered over the demand for comprehensive federal reform of immigration policy. Activists called for a new framework of citizenship, arguing that immigrants deserved legal status based on their strong affiliation with American values. During the Obama administration, leaders were granted unprecedented political access and millions of dollars in support. The national spotlight, however, came with unforeseen pressures—growing inequalities between factions and restrictions on challenging mainstream views. Such tradeoffs eventually shattered the united front. The Immigrant Rights Movement tells the story of a vibrant movement to change the meaning of national citizenship, that ultimately became enmeshed in the system that it sought to transform.

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.