Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging zoonotic coronavirus. First identified in 2012, MERS-CoV has caused over 2460 infections and a fatality rate of about 35% in humans. Similar to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV likely originated from bats; however, different from SARS-CoV, which potentially utilized palm civets as its intermediate hosts, MERS-CoV likely transmits to humans through dromedary camels. Animal models, such as humanized mice and nonhuman primates, have been developed for studying MERS-CoV infection. Currently, there are no vaccines and therapeutics approved for the prevention and treatment of MERS-CoV infection, although a number of them have been developed preclinically or tested clinically. This book covers one editorial and 16 articles (including seven review articles and nine original research papers) written by researchers working in the field of MERS-CoV. It describes the following three main aspects: (1) MERS-CoV epidemiology, transmission, and pathogenesis; (2) current progress on MERS-CoV animal models, vaccines, and therapeutics; and (3) challenges and future prospects for MERS-CoV research. Overall, this book will help researchers in the MERS-CoV field to further advance their work on the virus. It also has important implications for other coronaviruses as well as viruses outside the coronavirus family with pandemic potentials.

The definitive reference for travel medicine, updated for 2020! "A beloved travel must-have for the intrepid wanderer." -Publishers Weekly "A truly excellent and comprehensive resource." -Journal of Hospital Infection The CDC Yellow Book offers everything travelers and healthcare providers need to know for safe and healthy travel abroad. This 2020 edition includes: · Country-specific risk guidelines for yellow fever and malaria, including expert recommendations and 26 detailed, country-level maps · Detailed maps showing distribution of travel-related illnesses, including dengue, Japanese encephalitis, meningococcal meningitis, and schistosomiasis · Guidelines for self-treating common travel conditions, including altitude illness, jet lag, motion sickness, and travelers' diarrhea · Expert guidance on food and drink precautions to avoid illness, plus water-disinfection techniques for travel to remote destinations · Specialized guidelines for non-leisure travelers, study abroad, work-related travel, and travel to mass gatherings · Advice on medical tourism, complementary and integrative health approaches, and counterfeit drugs · Updated guidance for pre-travel consultations · Advice for obtaining healthcare abroad, including guidance on different types of travel insurance · Health insights around 15 popular tourist destinations and itineraries · Recommendations for traveling with infants and children · Advising travelers with specific needs, including those with chronic medical conditions or weakened immune systems, health care workers, humanitarian aid workers, long-term travelers and expatriates, and last-minute travelers · Considerations for newly arrived adoptees, immigrants, and refugees Long the most trusted book of its kind, the CDC Yellow Book is an essential resource in an ever-changing field -- and an ever-changing world.

Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging zoonotic coronavirus. First identified in 2012, MERS-CoV has caused over 2460 infections and a fatality rate of about 35% in humans. Similar to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV likely originated from bats; however, different from SARS-CoV, which potentially utilized palm civets as its intermediate hosts, MERS-CoV likely transmits to humans through dromedary camels. Animal models, such as humanized mice and nonhuman primates, have been developed for studying MERS-CoV infection. Currently, there are no vaccines and therapeutics approved for the prevention and treatment of MERS-CoV infection, although a number of them have been developed preclinically or tested clinically. This book covers one editorial and 16 articles (including seven review articles and nine original research papers) written by researchers working in the field of MERS-CoV. It describes the following three main aspects: (1) MERS-CoV epidemiology, transmission, and pathogenesis; (2) current progress on MERS-CoV animal models, vaccines, and therapeutics; and (3) challenges and future prospects for MERS-CoV research. Overall, this book will help researchers in the MERS-CoV field to further advance their work on the virus. It also has important implications for other coronaviruses as well as viruses outside the coronavirus family with pandemic potentials.

Over the last nine years, FAO, WHO and WOAH have worked with Member States, public health professionals and experts across multiple sectors and technical disciplines to improve preparedness and response capacities for MERS-CoV and other high threat zoonotic pathogens around the world. This work continues to bring together public health and animal health experts from affected and at-risk countries, scientists, and subject matter experts of high threat respiratory pathogens to review the latest scientific evidence on MERS-CoV and improve multi-sectoral collaboration. As a follow-up to previous technical meetings on MERS-CoV hosted by FAO, WHO and WOAH, a Global Technical Meeting was convened virtually on 15-16 November 2021 to share the latest findings from accelerated efforts to implement the MERS-CoV public health research agenda and research and development (R&D) road map, in the context of the ongoing COVID-19 pandemic. This documents presents a summary of the presentations and discussions.

This volume provides various techniques and methodologies currently used in the study of MERS-CoV. Chapters are divided into four parts detailing evolution and entry of MERS-coronavirus, genetic alteration and structural determination of MERS-coronavirus proteins, quantitation of virus and anti-viral factors, and mouse models for MERS -coronavirus. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, MERS Coronavirus: Methods and Protocols aims to ensure successful results in the further study of this vital field.

"The MERS-CoV Mastery Bible: Your Blueprint for Complete MERS-CoV Management" is a comprehensive guide offering a structured approach to understanding, managing, and recovering from Middle East Respiratory Syndrome Coronavirus (MERS-CoV). Beginning with the emergence of MERS-CoV and its virology, the book simplifies the complex structure of the virus and details transmission pathways. It equips readers with knowledge to recognize symptoms and provides insight into diagnosis protocols and the epidemiology of MERS-CoV. The medical management section covers first-line treatment options, antiviral medications, supportive care practices, innovative therapies, and the nuances of recovery and rehabilitation. Holistic health perspectives explore nutritional support for immunity, herbal remedies, the role of exercise, stress management techniques, and integrative medicine approaches. Readers are guided to create a personalized management plan, set realistic goals, and adapt daily routines for wellness. Long-term management considerations, self-help techniques, and building a robust support system are addressed, emphasizing mind-body techniques for enhanced recovery. The book delves into dietary considerations and provides recipes tailored for MERS-CoV patients, focusing on foods to boost immunity and anti-inflammatory benefits. Psychological impact and mental health strategies, including managing anxiety and depression, are discussed. Navigating the healthcare system, family dynamics, and seeking professional help post-recovery are also explored. This comprehensive guide aims not only to educate but empower individuals in their journey toward complete MERS-CoV management.