A convenient compact textbook that fits snugly into your scrubs pocket. Developed at McMaster University, the birthplace of evidence-based medicine (EBM) and one of the world's top universities, in cooperation with over 300 highly renowned scientists from North America and Poland.

Novel Psychoactive Substances: Classification, Pharmacology and Toxicology, Second Edition provides readers with a comprehensive examination on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." The book covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance and a discussion of their associated acute and chronic harm and toxicity. This second edition addresses drugs new to the scene, with completely updated and revised chapters. Written by international experts in the field, this multi-authored book is an essential reference for scientists, clinicians, academics, and regulatory and law enforcement professionals. - Includes chapters written by international experts in the field - Presents a comprehensive overview on the classification, detection, availability and supply of novel psychoactive substances, in addition to the pharmacology and toxicology associated with the substance - Offers a single source for all interested parties working in this area, including scientists, academics, clinicians, law enforcement and regulatory agencies - Provides a full treatment of novel psychoactive substances that have recently emerged onto the recreational drug scene, including amphetamines and the synthetic cannabinoid receptors in 'spice' and 'K2'

The accompanying CD-ROM contains clinical examples, critical appraisals and background papers.

Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. - First edition won Best Book in Medical Science Award from the Association of American Publishers - Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias - A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references

The new edition of this comprehensive guide to internal medicine for trainees, has been fully revised to provide the latest information and advances in the field. Each section covers the pathophysiology, signs and symptoms, investigation techniques, diagnosis and treatment options of clinical syndromes and diseases in a different organ system of the body, including the central nervous system, respiratory system, endocrine system, skin, blood, kidneys and much more. Topics have been thoroughly updated and new chapters on general physical examination and examination of the neurological, respiratory and gastrointestinal systems, have been added to the fourth edition. Clinical photographs, illustrations and tables further enhance the practical text. Key points Fully revised, new edition providing trainees with the latest advances in internal medicine Covers numerous diseases and disorders in all organ systems Fourth edition includes new chapters on physical examination Previous edition (9780729540810) published in 2015

- Chapters have been rearranged and often split to work towards one chapter-one lecture model so that the text is linked to curriculum objectives which appeals to both students and faculty. - Narrative length has been reduced while ensuring the original flow and explanation of concepts is not affected. - Updated Learning Objectives (e.g. Applied physiology of the Renal System) and Glossary of Terms in the beginning of every chapter. - Short, easy-to-read, masterfully edited chapters and a user-friendly full-color design facilitates better learning and retention. - Features expanded clinical coverage including obesity, metabolic and cardiovascular disorders, Alzheimer's disease, and other degenerative diseases. - Complex Concepts/Processes are summarized in flowcharts/flow diagram for better understanding. - Contains more than 1000 carefully crafted diagrams and drawings ensures better understanding of Physiology. - Offers Clinically Oriented perspective - bridging basic physiology with pathophysiology, including cellular and molecular mechanism important for Clinical medicine. - Updated throughout based on the Guyton and Hall Textbook of Physiology 14th edition to reflect the latest knowledge in the field. - The information of the book has been updated to include all areas of the new MCI curriculum (these are either embedded within the existing chapters or as several new chapters at the end of the book).

This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.