Combining experts from the medical and materials sciences, the Institute considered current concepts in medical and materials sciences as they relate to implantable prostheses in orthopedic surgical practice. The syllabus included theory and applications of materials properties, physiological function, and host response to metal and non-metal materials. Total hip prostheses are the most common orthopedic device implanted today involved in over 200,000 operations. Failures occur at the rate of 10~-40~ at ~ to 10 years. Failures are due to loosening, infection, fracture of femoral components, or destruction of the pe 1 vi c components .' All these, and other problems related to the implantation of the devices, the surgical procedures, and device pathology, were. discussed in light of current, as well as, emerging technologies and scientific knowledge. Repeatedly, scientists designing prostheses became aware of a lack of understanding of physiological phenomena associated with biocompatibility; the interchange among practising physicians, basic scientists, and pathologists at this Institute was appreciated. We thank all the contributors and participants for their effort. Thanks are also due to the personnel of the Scientific Affairs Division of NATO. The daily routines of running the Institute were greatly facilitated by the efforts of Pedro Cuevas, M.D, Jose Gutierrez Diaz, M.D, and Dr. Hanita Kossowsky. The devoted help of Nir Kossovsky, M.D, in setting the conference and in editing this book, is sincerely appreci ated.

Advances in Materials Science and Implant Orthopedic Surgery brings together experts from major university hospitals, materials scientists specializing in bio-materials, and development engineers working for implant manufacturers to address such issues as: mechanisms of fixation; foreign-body immune response; generation and consequences of ionic and wear debris; materials selection, design and manufacturing schemes; and surgical techniques to maximize the safety and efficacy of the devices.

The book contains six chapters and covers topics dealing with biomedical applications of titanium alloys, surface treatment, relationships between microstructure and mechanical and technological properties, and the effect of radiation on the structure of the titanium alloys.

Structural Biomaterials: Properties, Characteristics, and Selection serves as a single point of reference to digest current research and develop a deeper understanding in the field of biomaterials engineering. This book uses a materials-focused approach, allowing the reader to quickly access specific, detailed information on biomaterials characterization and selection. Relevant to a range of readers, this book provides holistic coverage of the broad categories of structural biomaterials currently available and used in medical applications, highlighting the property requirements for structural biomaterials, their biocompatibility performance and their safety regulation in key categories such as metals, ceramics and polymers. The materials science perspective of this text ensures the content is accessible even to those without an extensive background in applied medicine, positioning this text not just for students, but as an overview and reference for researchers, scientists and engineers entering the field from related materials science disciplines. - Provides a unique, holistic approach, covering key biomaterials categories in one text, including metals, ceramics and polymers - Discusses advantages, disadvantages, biocompatibility performance and safety regulations, allowing for accurate materials selection in medical applications - Utilizes a materials science perspective, allowing those without an extensive applied medical background to learn about the field

Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. - Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area - Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing - Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges - Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites

With the constant evolution of implant technology, and improvement in the production of allograft and bone substitutes, the armamentarium of the orthopaedic surgeon has significantly expanded. In particular, the recent involvement of nanotechnologies opens up the possibilities of new approaches in the interactive interfaces of implants. With many important developments occurring since the first edition of this well-received book, this updated resource informs orthopaedic practitioners on a wide range of biomechanical advances in one complete reference guide. Biomechanics and Biomaterials in Orthopedics, 2nd edition compiles the most prominent work in the discipline to offer newly-qualified orthopedic surgeons a summary of the fundamental skills that they will need to apply in their day-to-day work, while also updating the knowledge of experienced surgeons. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also providing an important basis for graduate and postgraduate learning.

Written by respected experts in the field, Biomaterials in Orthopedics discusses bioabsorbable biomaterials for bone repair, nondegradable materials in orthopaedics and delivery systems. Topics in this text include biocompatibility and the biomaterial/tissue interface; self-reinforced bioabsorbable devices and guided regeneration; bone substitutes,