"A good companion for those with a science background interested in learning more about human genetics." —Booklist Thanks to the popularity of personal genetic testing services, it's now easier than ever to get information about our own unique DNA—but who does this information really benefit? And, as genome editing and gene therapy transform the healthcare landscape, what do we gain—and what might we give up in return? Inside each of your cells is the nucleus, a small structure that contains all of the genetic information encoded by the DNA inside, your genome. Not long ago, the first human genome was sequenced at a cost of nearly $3 billion; now, this same test can be done for about $1,000. This new accessibility of genome sequence information creates huge potential for advances in how we understand and treat disease, among other things. It also raises significant concerns regarding ethics and personal privacy. In Mapping Humanity: How Modern Genetics Is Changing Criminal Justice, Personalized Medicine, and Our Identities, cellular biology expert Joshua Z. Rappoport provides a detailed look at how the explosion in genetic information as a result of cutting-edge technologies is changing our lives and our world. Inside, discover: • An in-depth look at how your personal genome creates the unique individual that you are • How doctors are using DNA sequencing to identify the underlying genetic causes of disease • Why the field of gene therapy offers amazing potential for medical breakthroughs—and why it's taking so long • The fantastic potential—and troubling concerns—surrounding genome editing • The real impact—and validity—of popular personal genetic testing products, such as 23andMe • Details of how molecular biology and DNA are changing the criminal justice system • Facts you should know about Genetically Modified Organisms (GMOs) Throughout, in compelling, accessible prose, Rappoport explores the societal, ethical, and economic impacts of this new era. Offering a framework for balancing the potential risks and benefits of genetic information technologies and genetic engineering, Mapping Humanity is an indispensable guide to navigating the possibilities and perils of our gene-centric future.

Until just a few years ago, we knew surprisingly little about the 150,000 or so years of human existence before the advent of writing. Some of the most momentous events in our past - including our origins, our migrations across the globe, and our acquisition of language - were veiled in the uncertainty of 'prehistory'. That veil is being lifted at last by geneticists and other scientists. Mapping Human History is nothing less than an astonishing 'history of prehistory'. Steve Olson travelled through four continents to gather insights into the development of humans and our expansion throughout the world. He describes, for example, new thinking about how centres of agriculture sprang up among disparate foraging societies at roughly the same time. He tells why most of us can claim Julius Caesar and Confucius among our forebears. He pinpoints why the ways in which the story of the Jewish people jibes with, and diverges from, biblical accounts. And using very recent genetic findings, he explodes the myth that human races are a biological reality.

There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

The past few years have seen a revolution in our ability to map whole genome DNA from ancient humans. With the ancient DNA revolution, combined with rapid genome mapping of present human populations, has come remarkable insights into our past. This important new data has clarified and added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up some remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations existing today are mixes of ancient ones, as well as in many cases carrying a genetic component from Neanderthals, and, in some populations, Denisovans. David Reich, whose team has been at the forefront of these discoveries, explains what the genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial 'purity', or even deep and ancient divides between peoples. Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should celebrate our rich diversity, and recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?

An examination of the implications for society of rapidly advancing artificial intelligence systems, combining a humanities perspective with technical analysis; includes exercises and discussion questions. AI and Humanity provides an analytical framing and a common language for understanding the effects of technological advances in artificial intelligence on society. Coauthored by a computer scientist and a scholar of literature and cultural studies, it is unique in combining a humanities perspective with technical analysis, using the tools of literary explication to examine the societal impact of AI systems. It explores the historical development of these technologies, moving from the apparently benign Roomba to the considerably more sinister semi-autonomous weapon system Harpy. The book is driven by an exploration of the cultural and etymological roots of a series of keywords relevant to both AI and society. Works examined range from Narrative of the Life of Frederick Douglass, given a close reading for its themes of literacy and agency, to Simon Head's critique of the effects of surveillance and automation on the Amazon labor force in Mindless. Originally developed as a textbook for an interdisciplinary humanities-science course at Carnegie Mellon, AI & Humanity offers discussion questions, exercises (including journal writing and concept mapping), and reading lists. A companion website provides updated resources and a portal to a video archive of interviews with AI scientists, sociologists, literary theorists, and others.

300 stunning maps from all periods and from all around the world, exploring and revealing what maps tell us about history and ourselves. Selected by an international panel of cartographers, academics, map dealers and collectors, the maps represent over 5,000 years of cartographic innovation drawing on a range of cultures and traditions. Comprehensive in scope, this book features all types of map from navigation and surveys to astronomical maps, satellite and digital maps, as well as works of art inspired by cartography. Unique curated sequence presents maps in thought-provoking juxtapositions for lively, stimulating reading. Features some of the most influential mapmakers and institutions in history, including Gerardus Mercator, Abraham Ortelius, Phyllis Pearson, Heinrich Berann, Bill Rankin, Ordnance Survey and Google Earth. Easy-to-use format, with large reproductions, authoritative texts and key caption information, it is the perfect introduction to the subject. Also features a comprehensive illustrated timeline of the history of cartography, biographies of leading cartographers and a glossary of cartographic terms.

Jane Yolen, the bestselling and award-winning author of The Devil's Arithmetic, returns to World War II and the Holocaust with this timely and necessary novel. It's 1942 in Poland, and the world is coming to pieces. At least that's how it seems to Chaim and Gittel, twins whose lives feel like a fairy tale torn apart, with evil witches, forbidden forests, and dangerous ovens looming on the horizon. But in all darkness there is light, and the twins find it through Chaim's poetry and the love they have for each other. Like the bright flame of a Yahrzeit candle, his words become a beacon of memory so that the children and grandchildren of survivors will never forget the atrocities that happened during the Holocaust. Filled with brutality and despair, this is also a story of poetry and strength, in which a brother and sister lose everything but each other. Nearly thirty years after the publication of her award-winning and bestselling The Devil's Arithmetic and Briar Rose, Yolen once again returns to World War II and captivates her readers with the authenticity and power of her words. Perfect for fans of Markus Zuzak's The Book Thief and Ruta Sepetys's Salt to the Sea.