This issue of Thoracic Surgery Clinics, guest edited by Dr. Bryan M. Burt, is devoted to Malignant Pleural Mesothelioma. Dr. Burt has assembled expert authors to review the following topics: Biomarkers for the Diagnosis and Monitoring of Malignant Pleural Mesothelioma; Taken Together: Effective Multimodal Approaches for Malignant Pleural Mesothelioma; Pleurectomy/Decortication for Malignant Pleural Mesothelioma; Preoperative Identification of Benefit from Surgery for Malignant Pleural Mesothelioma; The Role of Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma; The Molecular Basis of Malignant Pleural Mesothelioma; Radiation Therapy for Malignant Pleural Mesothelioma; The Staging of Malignant Pleural Mesothelioma; Intraoperative Adjuncts for Malignant Pleural Mesothelioma: The Fourth Dimension; The Pathology of Malignant Pleural Mesothelioma; and more!

This issue of Thoracic Surgery Clinics of North America, guest edited by Dr. Michael Lanuti, is devoted to Current Controversies in Thoracic Surgery. Dr. Lanuti has assembled expert authors to review the following topics: Management of Stage IIIA Non-Small Cell Lung Cancer; Management of Oligometastatic Non-Small Cell Lung Cancer; Current Treatment of Mesothelioma (Extrapleural Pneumonectomy or Pleurectomy); Stents as Primary Therapy for Esophageal Perforation; Lymph Node Dissection and Pulmonary Metastectomy; Mediastinal Staging: Endobronchial Ultrasound or Mediastinoscopy; Induction Therapy for Esophageal Cancer; Appropriate Surgical Treatment of Stage I Non-Small Cell Lung Cancer; Stereotactic Body Radiotherapy for Stage I Non-Small Cell Lung Cancer; Benefit of Plication for Paralyzed Diaphragm; Video-assisted Thoracoscopic Surgery (VATS) Sympathectomy for Hyperhidrosis; Induction Therapy for Thymoma, and more!

This issue of Thoracic Surgery Clinics, guest edited by Drs. Dean Donahue and Hugh G. Auchincloss, is devoted to Thoracic Outlet Syndrome. Drs. Donahue and Auchincloss have assembled expert authors to review the following topics: Embryology and Anatomy of the Thoracic Outlet; Evaluation of Patients with Neurogenic Thoracic Outlet Syndrome; Reoperation for Persistent or Recurrent Neurogenic Thoracic Outlet Syndrome; Surgical Technique: Supraclavicular First Rib Resection; Evaluation and Management of Venous Thoracic Outlet Syndrome; How Common is Thoracic Outlet Syndrome?; Surgical Technique: Minimally Invasive First Rib Resection; Radiographic Evaluation of Thoracic Outlet Syndrome; Evaluation and Management of Arterial Thoracic Outlet Syndrome; and more!

This issue of Thoracic Surgery Clinics, guest edited by Drs. Vincenzo Ambrogi and Tommaso Mineo, is devoted to Nonintubated Thoracic Surgery. Drs. Ambrogi and Mineo have assembled expert authors to review the following topics: Technical issues and patient safety in nonintubated thoracic anesthesia; Management of primary and secondary pneumothorax in nonintubated VATS; Treatment of pleural effusions with nonintubated VATS; Nonintubated VATS for chest infections; Nonintubated VATS lung biopsy for interstitial lung disease; Nonintubated VATS wedge resection of peripheral early lung cancer; Anatomical segmentectomy in nonintubated VATS; VATS lobectomy for lung cancer in nonintubated anesthesia; Nonintubated VATS tracheal and bronchial sleeve resection for lung cancer; Nonintubated tracheal surgery; Management of intraoperative crisis during nonintubated thoracic surgery; Team training for nonintubated thoracic surgery; and more!

This book provides health professionals and scientists with a comprehensive overview of the mesothelioma - an asbestos induced malignancy. It includes chapters on epidemology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, and radiotherapy as well as the molecular biology and future therapies.

This book offers an updated review of malignant mesothelioma, including the latest advances in our understanding of its genetic control and molecular biology, as well as pre-clinical and clinical research. It also presents state-of-the-art diagnostic approaches and therapeutic options, and an open discussion on the future prospects for patient management. Malignant mesothelioma is an enormous global health problem related to asbestos exposure. Despite the best efforts of scientists and oncologists, the prognosis for those affected remains poor. Due to anatomical characteristics and non-specific symptoms, the diagnosis of mesothelioma at an early stage is often difficult, while surgery and radiotherapy are only of limited use, even if some multimodality approaches seem promising. In turn, medical treatments are sometimes successful in tumor control, but have little impact on overall survival. However, advances in our understanding of the disease’s biology, together with the availability of new drugs and combinations, make mesothelioma an essential and highly topical field for pre-clinical and clinical studies. This book is subdivided into four parts: epidemiology and preclinical data, diagnosis, therapy, and extrathoracic mesothelioma. It highlights the progress made in a variety of areas – e.g. in vitro and in vivo experimental models, genetics, environment, biomarkers, targeting agents, immunotherapy, metabolic imaging and ongoing clinical trials – and describes the standard clinical management of mesothelioma patients, including those with extra-thoracic localizations. Given its scope, the book offers an invaluable tool for researchers, oncologists and clinicians alike.

This issue of Surgical Oncology Clinics of North America, guest edited by Drs. Usman Ahmad and Sudish Murthy, is devoted to Emerging Therapies in Thoracic Malignancies. Drs. Ahmad and Murthy has assembled expert authors to review the following topics: Mediastinal Germ Cell Tumors: Updates in Diagnosis and Management; Multidisciplinary Evaluation and Management of Early Stage Esophageal Cancer; Evaluation of Risk for Thoracic Surgery; Mesothelioma: Updates in Staging and Management; Chest Wall Sarcoma: When and Who to Resect and How to Reconstruct; Management of Locally Advanced Esophageal Cancer; Locally Advanced Lung Cancer and Salvage Resections; Siewert III Adenocarcinoma: Still Searching for the Right Treatment Combination; Current Indications for Pulmonary Metastasectomy; Lung Cancer Screening; Thymic Malignancies: Updates in Treatment and Staging; Intra-operative Detection and Assessment of Lung Nodules; Targeted Therapies, Immunotherapy and T-Cell Therapy in Lung Cancer; and more!