Quyển sách này nhằm hỗ trợ tín đồ trong việc phát triển thời gian phấn hưng buổi sáng hằng ngày với Chúa trong lời Ngài. Đồng thời, sách cũng giúp ôn lại phần nào kì Huấn luyện bán niên được tổ chức vào ngày 20-25 tháng 12 năm 2021 về “Nghiên cứu kết tinh sách 1 và 2 Sa-mu-ên.” Qua sự tiếp xúc mật thiết với Chúa trong lời Ngài, tín đồ có thể được cấu tạo bằng sự sống và lẽ thật, bởi đó được trang bị để nói tiên tri trong các buổi nhóm của Hội thánh, dẫn đến xây dựng Thân thể Đấng Christ.

Quyển sách này nhằm hỗ trợ tín đồ trong việc phát triển thời gian phấn hưng buổi sáng hằng ngày với Chúa trong lời Ngài. Đồng thời, sách cũng giúp ôn lại phần nào kì Huấn luyện bán niên được tổ chức vào ngày 20-25 tháng 12 năm 2021 về “Nghiên cứu kết tinh sách 1 và 2 Sa-mu-ên.” Qua sự tiếp xúc mật thiết với Chúa trong lời Ngài, tín đồ có thể được cấu tạo bằng sự sống và lẽ thật, bởi đó được trang bị để nói tiên tri trong các buổi nhóm của Hội thánh, dẫn đến xây dựng Thân thể Đấng Christ.

It is now widely acknowledged that at the beginning of this century Claude von Pirquet first pointed out that a viral disease, i. e. , measles, resulted in an anergy or depression of preexisting immune response, namely, delayed continuous hypersensitivity to PPD derived from Mycobacterium tuberculosis. Thereafter ob servations that viral infections may result in immunosuppression have been recorded by many clinicians and infectious disease investigators for six or seven decades. Nevertheless, despite sporadic reports that infectious diseases caused by viruses may result in either transient or prolonged immunodepression, investigation of this phenomenon languished until the mid-1960s, when it was pointed out that a number of experimental retroviral infections of mice with tumor viruses may result in marked immunosuppression. However, it was not until the recognition of the new epidemic of acquired immunodeficiency syn drome (AIDS) caused by the human immunodeficiency virus and related vi ruses that acquired immunodeficiencies associated with virus infection became general knowledge among biomedical investigators as well as the lay public. A number of reviews published during the past decade or so pointed out that numerous viruses may affect humoral and cellular immune responses. Furthermore, expanding knowledge about the nature and mechanisms of both humoral and cellular immunity and pathogenesis of viral infections has pro vided clinical and experimental models for investigating in depth how and why viruses of man and animals profoundly affect immune responses.

Chemoprevention of Cancer guides you through the exciting new field of cancer chemoprevention. It covers epidemiology, known chemopreventive compounds, development of new chemopreventive agents, specific examples of preventive agents and their mechanisms of action, and current prevention clinical trials.

This volume represents the first attempt to present in one place the clinical syndromes and the pathophysiologic basis for the "resistance states" to each of the classes of steroid hormones. Glucocorticoids, mineralocorticoids, androgens, estrogens, progesterone and vitamin D have widely diverse roles ranging from the control of homeostasis to reproduction and bone formation. They are similar in that they share a chemical structure and that their action is in the cell nucleus where they induce transcription of specific genes leading to synthesis of function-specific proteins. Clinical syndromes of steroid hormone resistance to androgens (complete and partial testicular feminization), aldosterone (pseudo hypoaldosteronism) and vitamin D (vitamin D-dependent rickets type II) have been known for many years. Progesterone and glucocorticoid resistance syndromes have been described only recently. Resistance to estrogens has not been reported in man or in animals. It is hoped that a detailed reexamination of what is known about each of these conditions at the clinical and molecular levels will enhance our understanding of the function of these hormones and their mechanisms of action. New insight and research initiatives should result. G.P. Chrousos D.L. Loriaus M.B. Lipsett vii ACKNOWLEDGMENTS The contents of this volume are based in part on the proceedings of an International Conference held in Bethesda in the summer of 1984. This conference was sponsored by the National Institute of Child Health and Human Development, Bethesda, Maryland.

Leading scientists discuss in this book how we can not only detect cancer at an early stage, but even work toward preventing it altogether in the future. They consider genetic and non-genetic causes of cancer, the development of new detection methods, as well as other factors that will improve our understanding of the basic mechanisms of carcinogenesis.