Details methods for computing valid limits of detection. Clearly explains analytical detection limit theory, thereby mitigating incorrect detection limit concepts, methodologies and results Extensive use of computer simulations that are freely available to readers Curated short-list of important references for limits of detection Videos, screencasts, and animations are provided at an associated website, to enhance understanding Illustrated, with many detailed examples and cogent explanations

Kontaminationen so früh wie möglich erkennen und damit so früh wie möglich beseitigen: Statistische Methoden, die diesem Ziel dienen, werden hier vorgestellt. Die besprochenen Strategien zum Nachweis und zur Quantifizierung von Schadstoffen lassen sich auf alle Umweltkompartimente anwenden. Praktische Details werden anhand von Fallstudien anschaulich erläutert.

Clinical chemical data are used in many ways in the prevention, diagnosis and treatent of disease. It is obviously essential that the properties measured in the clinic and the results communicated from the laboratory to the clinician are correctly understood. The new Silver Book contains internationally accepted conventions in terminology and nomenclature in clinical chemistry, and is the key to clarity and precision in communication in the discipline

For decades gas chromatography has been and will remain an irreplaceable analytical technique in many research areas for both quantitative analysis and qualitative characterization/identification, which is still supplementary with HPLC. This book highlights a few areas where significant advances have been reported recently and/or a revisit of basic concepts is deserved. It provides an overview of instrumental developments, frontline and modern research as well as practical industrial applications. The topics include GC-based metabolomics in biomedical, plant and microbial research, natural products as well as characterization of aging of synthetic materials and industrial monitoring, which are contributions of several experts from different disciplines. It also contains best hand-on practices of sample preparation (derivatization) and data processing in daily research. This book is recommended to both basic and experienced researchers in gas chromatography.

The purpose of this book is to present a state of art summary of current knowledge of methods of assessment of radionuclides in the terrestrial and marine environments. It cover the traditional methods of radioactivity measurements such as radiometrics techniques, but also recent developments in the mass spectrometry sector. The book starts with a short preface introducing the subject of the book, summarising content and philosophy of the book, as well as the most important historical achievements. The scientific topics are introduced by description of sampling methods, optimisation of sampling sites and sampling frequency. The recent developments in radiochemical separation methods using chromatography resins for the treatment of actinides, transuranics and other groups of radioelements are also described. No other book is available covering all aspects of environmental radioactivity measurements, although remarkable progress has been made in detection techniques over the last ten years. At present the new methods enable to carry out investigations which were not possible before, either because of lack of sensitivity or because of the fact that they required too large samples.