The fascinating story of two men, 200 years apart, who risked ridicule and ruin for the ideas they believed in. In 18th-century France Jean Baptiste de Lamarck ignored scientific tradition and developed the first theory of evolution. But 50 years later Charles Darwin published his own work and Lamarck became a laughing stock. Contemporary academic Ted Steele was similarly mocked and nearly ruined for supporting Lamarck's idea that inherited characteristics could be passed on. Now cutting edge discoveries have vindicated him at last. Their story is a rollercoaster ride of intelligence, stubborn vision, despair and vindication.

A riveting explanation of epigenetics, offering startling insights into our inheritable traits. In the 1700s, Jean-Baptiste Lamarck first described epigenetics to explain the inheritance of acquired characteristics; however, his theory was supplanted in the 1800s by Darwin's theory of evolution by natural selection through heritable genetic mutations. But natural selection could not adequately explain how rapidly species re-diversified and repopulated after mass extinctions. Now advances in the study of DNA and RNA have resurrected epigenetics, which can create radical physical and physiological changes in subsequent generations by the simple addition of a single small molecule, thus passing along a propensity for molecules to attach in the same places in the next generation. Epigenetics is a complex process, but paleontologist and astrobiologist Peter Ward breaks it down for general readers, using the epigenetic paradigm to reexamine how the history of our species-from deep time to the outbreak of the Black Plague and into the present-has left its mark on our physiology, behavior, and intelligence. Most alarming are chapters about epigenetic changes we are undergoing now triggered by toxins, environmental pollutants, famine, poor nutrition, and overexposure to violence. Lamarck's Revenge is an eye-opening and provocative exploration of how traits are inherited, and how outside influences drive what we pass along to our progeny.

Does the inheritance of acquired characteristics play a significant role in evolution? In this book, Eva Jablonka and Marion J. Lamb attempt to answer that question with an original, provocative exploration of the nature and origin of hereditary variations. Starting with a historical account of Lamarck's ideas and the reasons they have fallen in disrepute, the authors go on to challenge the prevailing assumption that all heritable variation is random and the result of variation in DNA base sequences. They also detail recent breakthroughs in our understanding of the molecular mechanisms underlying inheritance--including several pathways not envisioned by classical population genetics--and argue that these advances need to be more fully incorporated into mainstream evolutionary theory. Throughout, the book offers a new look at the evidence for and against the hereditability of environmentally induced changes, and addresses timely questions about the importance of non-Mendelian inheritance. A glossary and extensive list of references round out the book. Urging a reconsideration of the present DNA-centric view prevalent in the field, Epigentic Inheritance and Evolution will make fascinating and important reading for students and researchers in evolution, genetics, ecology, molecular biology, developmental biology, and the history and philosophy of science.

Jean-Baptiste Lamarck was a biological Janus, at once a highly competent taxonomist in a traditional mold and a bold, almost visionary, philosopher of nature who aspired to contrive an all-embracing "physics of the earth" by sheer force of intellect. Lamarck is generally remembered only for his ideas about the inheritance of acquired characters, ideas he did not originate or take special credit for, ideas that were only one part of his broad theory of evolution. In this, the first modern book-length study of Lamarck, Richard Burkhardt examines the origin and development of Lamarck's theory of organic evolution, the major theory prior to Darwin.

This text challenges the accepted theory on the genetic mechanism of evolution. The traditional neo-darwinian view is that we are at the mercy of our genes which we inherit, largely unchanged, from our parents, apart from random mutations which accumulate and lead to change over evolutionary time. The work shows that for one adaptive body system there is strong molecular genetic evidence that aspects of acquired immunities developed by parents during their lifetime may be passed on to their children. This gives new credibility to the Lamarckian heresy - the notion of the inheritance of acquired characteristics, which has, until now, been refuted.

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.