Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic sequence under investigation. The AGT Cytogenetics Laboratory Manual, Fourth Edition offers a comprehensive description of the diagnostic tests offered by the clinical laboratory and explains the science behind them. One of the most valuable assets is its rich compilation of laboratory-tested protocols currently being used in leading laboratories, along with practical advice for nearly every area of interest to cytogeneticists. In addition to covering essential topics that have been the backbone of cytogenetics for over 60 years, such as the basic components of a cell, use of a microscope, human tissue processing for cytogenetic analysis (prenatal, constitutional, and neoplastic), laboratory safety, and the mechanisms behind chromosome rearrangement and aneuploidy, this edition introduces new and expanded chapters by experts in the field. Some of these new topics include a unique collection of chromosome heteromorphisms; clinical examples of genomic imprinting; an example-driven overview of chromosomal microarray; mathematics specifically geared for the cytogeneticist; usage of ISCN’s cytogenetic language to describe chromosome changes; tips for laboratory management; examples of laboratory information systems; a collection of internet and library resources; and a special chapter on animal chromosomes for the research and zoo cytogeneticist. The range of topics is thus broad yet comprehensive, offering the student a resource that teaches the procedures performed in the cytogenetics laboratory environment, and the laboratory professional with a peer-reviewed reference that explores the basis of each of these procedures. This makes it a useful resource for researchers, clinicians, and lab professionals, as well as students in a university or medical school setting.

So much has been learned about RNA in the past ten years that the ability to purify, analyze, and manipulate RNA molecules is now essential in all kinds of bioscience. Initiating RNA research can be intimidating but the new book RNA: A Laboratory Manualprovides a broad range of up-to-date techniques presented in a functional framework, so that any investigator can confidently handle RNA and carry out meaningful experiments, from the most basic to the highly sophisticated. Originating in three of the field's most prominent laboratories, this manual provides the necessary background and strategies for approaching any RNA investigation, as well as detailed protocols and extensive tips and troubleshooting information. It is required reading for every research laboratory in the life sciences.

Developed by three experts to coincide with geology lab kits, this laboratory manual provides a clear and cohesive introduction to the field of geology. Introductory Geology is designed to ease new students into the often complex topics of physical geology and the study of our planet and its makeup. This text introduces readers to the various uses of the scientific method in geological terms. Readers will encounter a comprehensive yet straightforward style and flow as they journey through this text. They will understand the various spheres of geology and begin to master geological outcomes which derive from a growing knowledge of the tools and subjects which this text covers in great detail.

Ideal for use with any introductory physics text, Loyd's PHYSICS LABORATORY MANUAL is suitable for either calculus- or algebra/trigonometry-based physics courses. Designed to help students develop their intuitive abilities in physics, the third edition has been updated to take advantage of modern equipment realities and to incorporate the latest in physics education research. In each lab, author David Loyd emphasizes conceptual understanding and includes a thorough discussion of physical theory to help students see the connection between the lab and the lecture. Each lab includes a set of pre-lab exercises, and many labs give students hands-on experience with statistical analysis. Equipment requirements are kept at a minimum to allow for maximum flexibility and to make the most of pre-existing lab equipment. For instructors interested in using some of Loyd's experiments, a customized lab manual is another option available through the Cengage Learning Custom Solutions program. Now, you can select specific experiments from Loyd's PHYSICS LABORATORY MANUAL, include your own original lab experiments, and create one affordable bound book. Contact your Cengage Learning representative for more information on our Custom Solutions program. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

This second edition laboratory manual was written to accompany Food Analysis, Fourth Edition, ISBN 978-1-4419-1477-4, by the same author. The 21 laboratory exercises in the manual cover 20 of the 32 chapters in the textbook. Many of the laboratory exercises have multiple sections to cover several methods of analysis for a particular food component of characteristic. Most of the laboratory exercises include the following: introduction, reading assignment, objective, principle of method, chemicals, reagents, precautions and waste disposal, supplies, equipment, procedure, data and calculations, questions, and references. This laboratory manual is ideal for the laboratory portion of undergraduate courses in food analysis.

Praise for Allen & Harper's "Laboratory Manual for Anatomy and Physiology " Connie Allen and Valerie Harper... have done an excellent job of preparing an A & P lab manual that students will appreciate and instructors will find easy to teach." "- - Moges Bizuneh, Ivy Tech State College - Indianapolis " I am very impressed with the quality and the readability of this lab manual." "- - Karen K. McLellan, Indiana University-Purdue University Fort Wayne " ... .this lab manual is an excellent one. It is well-written, has just the right amount of written text, and contains very good illustrations, photos, lab activities and questions." "- - Janet Lichti, Ivy Tech State College - Lafayette Also available PowerAnatomy, An Online Laboratory Manual Connie Allen, Valeria Harper, Susan Baxley ISBN: 0-471-44558-4 "PowerAnatomy combines over 100 of Primal's exquisitely detailed, 3D models of the human body, along with text, exercises, and review materials. Fetal Pig Dissection: A Laboratory Guide, 2nd Edition Connie Allen and Valerie Harper ISBN: 0-471-70138-6, Paper Cat Dissection: A Laboratory Guide, 2nd Edition Connie Allen and Valerie Harper ISBN: 0-471-70141-6, Paper

For the first time in over 20 years, a comprehensive collection of photographs and descriptions of species in the fungal genus Fusarium is available. This laboratory manual provides an overview of the biology of Fusarium and the techniques involved in the isolation, identification and characterization of individual species and the populations in which they occur. It is the first time that genetic, morphological and molecular approaches have been incorporated into a volume devoted to Fusarium identification. The authors include descriptions of species, both new and old, and provide protocols for genetic, morphological and molecular identification techniques. The Fusarium Laboratory Manual also includes some of the evolutionary biology and population genetics thinking that has begun to inform the understanding of agriculturally important fungal pathogens. In addition to practical “how-to” protocols it also provides guidance in formulating questions and obtaining answers about this very important group of fungi. The need for as many different techniques as possible to be used in the identification and characterization process has never been greater. These approaches have applications to fungi other than those in the genus Fusarium. This volume presents an introduction to the genus Fusarium, the toxins these fungi produce and the diseases they can cause. "The Fusarium Laboratory Manual is a milestone in the study of the genus Fusarium and will help bridge the gap between morphological and phylogenetic taxonomy. It will be used by everybody dealing with Fusarium in the Third Millenium." --W.F.O. Marasas, Medical Research Council, South Africa