From the award-winning author of Finding Mighty, a moving middle-grade novel about finding your place by following your heart Karthik Raghavan is good at remembering things. Like his bike routes. Or all the reasons he likes Juhi Shah—even if she doesn’t even know he exists. It doesn't help that she seems to have a crush on his arch nemesis, Jacob Donnell, whose only job is to humiliate Karthik (and get his name wrong). Then Karthik's luck changes when he secretly agrees to be in a play about the famous musician, Leonard Bernstein. But he can't tell his parents. The family store is in jeopardy, and they need him delivering groceries on his bike to help save it. His mom is also worried about the Financial Crisis, and she's convinced that studying hard and staying focused is the only way to succeed. But Karthik is having fun being Lenny. Besides, what if acting is Karthik’s special talent? And what if acting is the one way to catch Juhi Shah’s attention? With all the pressure from his family to succeed, will Karthik be able to really imagine and hope when he’s not sure what will happen next?

Along the train lines north of New York City, twelve-year-old neighbors Myla and Peter search for the link between Myla’s necklace and the disappearance of Peter’s brother, Randall. Thrown into a world of parkour, graffiti, and diamond-smuggling, Myla and Peter encounter a band of thugs who are after the same thing as Randall. Can Myla and Peter find Randall before it’s too late, and their shared family secrets threaten to destroy them all? Drawing on urban art forms and local history, Finding Mighty is a mystery that explores the nature of art and the unbreakable bonds of family.

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Animals make for terrible technology. The technological use of animals--making food, drugs, clothing, and cosmetics out of animal material--will cease. A cow takes over one year to grow, "wastes" over ninety percent of what it's fed, and cannot be innovated much further. After Meat explains the fundamental limits of animal technology in terms of physics and biology. Replacement technology such as microbial fermentation will surpass those limits. Eventually, we'll have food that is better in every way--in terms of taste, cost, nutrition, resource consumption, and ethics--because we won't use animals to produce it. Along the way, After Meat leads us through a veritable forest of adjacent topics. We wade into evolution and reductivism, broach consciousness and the Multiverse, dive into economics and policy, bounce from weather prediction to the problem of hunger to the morality of eating plants. In sum, we ineluctably conclude that our future has little room for animal technology, and that future will be better for it.

Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled “Transmucosal Absorption Enhancers in the Drug Delivery Field” aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.

Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. - Assesses the opportunities and challenges of nanotechnology-based drug delivery systems - Explores how nanotechnology is being used to create more efficient drug delivery systems - Discusses which nanomaterials make the best drug carriers

Nutrient Delivery: Nanotechnology in the Agri-Food Industry, Volume Five, discusses the fabrication, merits, demerits, applications, and bioavailability enhancement mechanisms of various nanodelivery systems. Recent developments in various nanodelivery systems are also highlighted. Volume 5 contains twenty chapters, prepared by outstanding international researchers from Argentina, Brazil, Canada, China, Croatia, India, Iran, Ireland, México, Pakistan, Portugal, Serbia, Sri Lanka, and the United States. In recent years, the delivery of micronutrients at nanoscale has been widely studied as these systems have the potential to improve bioavailability, enable controlled release and enhance stability of food bioactives to a greater extent. The nanodelivery systems typically consist of the food bioactive compound encapsulated and stabilized in food grade ingredients such as lipids, proteins or polysaccharides with diameters ranging from 10 nm to 1000 nm. Among these, the lipid based delivery systems such as nanoemulsions, solid lipid nanoparticles, nanoliposomes and micelles are widely studied for the delivery of lipophilic bioactive compounds. These delivery vehicles improve the solubility, permeability, stability and bioavailability of the lipophilic compounds thereby enhancing their potential for oral delivery and functional food development. On the other hand, the hydrophilic bioactives are delivered through protein, polysaccharide or biopolymer based colloidal nanosystems such as hydrogels, nanogels and polymer nanoparticles. The major concern other than solubility is the intestinal permeability of the micronutrients. For instance, the delivery system for compounds with poor intestinal permeability and low solubility need to be carefully designed using suitable lipids and surfactants. - Offers updated material for undergraduate and postgraduate students in food science, biotechnology, and related engineering fields - Provides a valuable resource of recent scientific progress, along with most known applications of nanomaterials in the food industry for researchers, engineers, and academics - Includes novel opportunities and ideas for developing or improving technologies in the food industry