Data mining provides a set of new techniques to integrate, synthesize, and analyze tdata, uncovering the hidden patterns that exist within. Traditionally, techniques such as kernel learning methods, pattern recognition, and data mining, have been the domain of researchers in areas such as artificial intelligence, but leveraging these tools, techniques, and concepts against your data asset to identify problems early, understand interactions that exist and highlight previously unrealized relationships through the combination of these different disciplines can provide significant value for the investigator and her organization.

Most life science researchers will agree that biology is not a truly theoretical branch of science. The hype around computational biology and bioinformatics beginning in the nineties of the 20th century was to be short lived (1, 2). When almost no value of practical importance such as the optimal dose of a drug or the three-dimensional structure of an orphan protein can be computed from fundamental principles, it is still more straightforward to determine them experimentally. Thus, experiments and observationsdogeneratetheoverwhelmingpartofinsightsintobiologyandmedicine. The extrapolation depth and the prediction power of the theoretical argument in life sciences still have a long way to go. Yet, two trends have qualitatively changed the way how biological research is done today. The number of researchers has dramatically grown and they, armed with the same protocols, have produced lots of similarly structured data. Finally, high-throu- put technologies such as DNA sequencing or array-based expression profiling have been around for just a decade. Nevertheless, with their high level of uniform data generation, they reach the threshold of totally describing a living organism at the biomolecular level for the first time in human history. Whereas getting exact data about living systems and the sophistication of experimental procedures have primarily absorbed the minds of researchers previously, the weight increasingly shifts to the problem of interpreting accumulated data in terms of biological function and bio- lecular mechanisms.

This timely book identifies and highlights the latest data mining paradigms to analyze, combine, integrate, model and simulate vast amounts of heterogeneous multi-modal, multi-scale data for emerging real-world applications in life science.The cutting-edge topics presented include bio-surveillance, disease outbreak detection, high throughput bioimaging, drug screening, predictive toxicology, biosensors, and the integration of macro-scale bio-surveillance and environmental data with micro-scale biological data for personalized medicine. This collection of works from leading researchers in the field offers readers an exceptional start in these areas.

"The amount of information collected on human behavior every day is staggering, and exponentially greater than at any time in the past. At the same time, we are inundated by stories of powerful algorithms capable of churning through this sea of data and uncovering patterns. These techniques go by many names - data mining, predictive analytics, machine learning - and they are being used by governments as they spy on citizens and by huge corporations are they fine-tune their advertising strategies. And yet social scientists continue mainly to employ a set of analytical tools developed in an earlier era when data was sparse and difficult to come by. In this timely book, Paul Attewell and David Monaghan provide a simple and accessible introduction to Data Mining geared towards social scientists. They discuss how the data mining approach differs substantially, and in some ways radically, from that of conventional statistical modeling familiar to most social scientists. They demystify data mining, describing the diverse set of techniques that the term covers and discussing the strengths and weaknesses of the various approaches. Finally they give practical demonstrations of how to carry out analyses using data mining tools in a number of statistical software packages. It is the hope of the authors that this book will empower social scientists to consider incorporating data mining methodologies in their analytical toolkits"--Provided by publisher.

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

Learn Data Mining by doing data mining Data mining can be revolutionary-but only when it's done right. The powerful black box data mining software now available can produce disastrously misleading results unless applied by a skilled and knowledgeable analyst. Discovering Knowledge in Data: An Introduction to Data Mining provides both the practical experience and the theoretical insight needed to reveal valuable information hidden in large data sets. Employing a "white box" methodology and with real-world case studies, this step-by-step guide walks readers through the various algorithms and statistical structures that underlie the software and presents examples of their operation on actual large data sets. Principal topics include: * Data preprocessing and classification * Exploratory analysis * Decision trees * Neural and Kohonen networks * Hierarchical and k-means clustering * Association rules * Model evaluation techniques Complete with scores of screenshots and diagrams to encourage graphical learning, Discovering Knowledge in Data: An Introduction to Data Mining gives students in Business, Computer Science, and Statistics as well as professionals in the field the power to turn any data warehouse into actionable knowledge. An Instructor's Manual presenting detailed solutions to all the problems in the book is available online.

Introduction to Data Science: Data Analysis and Prediction Algorithms with R introduces concepts and skills that can help you tackle real-world data analysis challenges. It covers concepts from probability, statistical inference, linear regression, and machine learning. It also helps you develop skills such as R programming, data wrangling, data visualization, predictive algorithm building, file organization with UNIX/Linux shell, version control with Git and GitHub, and reproducible document preparation. This book is a textbook for a first course in data science. No previous knowledge of R is necessary, although some experience with programming may be helpful. The book is divided into six parts: R, data visualization, statistics with R, data wrangling, machine learning, and productivity tools. Each part has several chapters meant to be presented as one lecture. The author uses motivating case studies that realistically mimic a data scientist’s experience. He starts by asking specific questions and answers these through data analysis so concepts are learned as a means to answering the questions. Examples of the case studies included are: US murder rates by state, self-reported student heights, trends in world health and economics, the impact of vaccines on infectious disease rates, the financial crisis of 2007-2008, election forecasting, building a baseball team, image processing of hand-written digits, and movie recommendation systems. The statistical concepts used to answer the case study questions are only briefly introduced, so complementing with a probability and statistics textbook is highly recommended for in-depth understanding of these concepts. If you read and understand the chapters and complete the exercises, you will be prepared to learn the more advanced concepts and skills needed to become an expert.