This textbook takes as a premise that, in order to make intelligent diagnosis and provide a rational treatment in disorders of the nervous system, it is necessary to develop the capacity to answer the basic questions of clinical neurology: (1) Where is the disease process located? (2) What is the nature of the disease process? The purpose of this textbook is to enable the medical student to acquire the basic information of the neurosciences and neurology and most importantly the ability to apply that information to the solution of clinical problems. The authors also suggest that hospital trips be a part of any Clinical Neurosciences Course so that the student can put into actual practice what he has learned in the classroom. We believe that this textbook will be of value to the student throughout the four years of the medical school curriculum. Medical, psychiatry and neurology residents may also find this text of value as an introduction or review.

This text focuses not only on localized diseases caused by infectious diseases, trauma, tumours, and vascular lesions within the central nervous system, but also these diseases within the systems of the brain and spinal cord. Over 250 real cases with associated MRI or CTs and any pathological findings from these patients illustrate numerous disorders and fully explain the nature of the pathology.

Each title in the new Integrated series focuses on the core knowledge in a specific basic science discipline, while linking that information to related concepts from other disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Bonus STUDENT CONSULT access is included! These concise and user-friendly references provide crucial guidance for the early years of medical training, as well as for exam preparation. Includes case-based questions at the end of each chapter Features a colour-coded format to facilitate quick reference and promote effective retention Offers access to STUDENT CONSULT! At www.studentconsult.com, you'll find an interactive community center with a wealth of additional resources!

This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader. The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.

Studying brain networks has become a truly interdisciplinary endeavor, attracting students and seasoned researchers alike from a wide variety of academic backgrounds. What has been lacking is an introductory textbook that brings together the different fields and provides a gentle introduction to the major concepts and findings in the emerging field of network neuroscience. Network Neuroscience is a one-stop-shop that is of equal use to the neurobiologist, who is interested in understanding the quantitative methods employed in network neuroscience, and to the physicist or engineer, who is interested in neuroscience applications of mathematical and engineering tools. The book spans 27 chapters that cover everything from individual cells all the way to complex network disorders such as depression and autism spectrum disorders. An additional 12 toolboxes provide the necessary background for making network neuroscience accessible independent of the reader's background. Dr. Flavio Frohlich wrote this book based on his experience of mentoring dozens of trainees in the Frohlich Lab, from undergraduate students to senior researchers. The Frohlich lab pursues a unique and integrated vision that combines computer simulations, animal model studies, human studies, and clinical trials with the goal of developing novel brain stimulation treatments for psychiatric disorders. The book is based on a course he teaches at UNC that has attracted trainees from many different departments, including neuroscience, biomedical engineering, psychology, cell biology, physiology, neurology, and psychiatry. Dr. Frohlich has consistently received rave reviews for his teaching. With this book he hopes to make his integrated view of neuroscience available to trainees and researchers on a global scale. His goal is to make the book the training manual for the next generation of (network) neuroscientists, who will be fusing biology, engineering, and medicine to unravel the big questions about the brain and to revolutionize psychiatry and neurology. - Easy-to-read, comprehensive introduction to the emerging field of network neuroscience - Includes 27 chapters packed with information on topics from single neurons to complex network disorders such as depression and autism - Features 12 toolboxes serve as primers to provide essential background knowledge in the fields of biology, mathematics, engineering, and physics

"Neurology is a quantitively small corner of medicine that, increasingly, occupies a position of outsized importance and distinction in both the practice of medicine and in the health and well-being of society. The Decade of the Brain came into public awareness in 1990 as an initiative of president George W. Bush involving the NIH and NIMH "to enhance public awareness of the benefits to be derived from brain research"(1). In the intervening 20 years since 1999, we have seen significant increases in understanding the myriad of neurological diseases that confront society"--