When Detective Inspector Stewart Gardener investigates the discovery of a body in a run-down Victorian property in the suburb of Rawston near Leeds, he knows he's in for a tough time: ashen faced police constables testify to that.Nothing could have prepared him for what lay ahead.The corpse is beyond recognition.Distraught residents, drug dealers, pornographers, and paedophiles add to his list of complications, especially when they're all hiding something.With little time to recuperate, a second body, bearing the same hallmark is found in the grounds of a small church in the center of Leeds.Gardener's already overburdened work schedule is stretched beyond endurance. Over the last six months, children have been going missing: the dead body of the third child having recently been found on waste ground - naked, has instigated a murder hunt.He now knows he needs to find a deranged serial killer, but are the cases linked?With a complex murder case to unravel, the last thing he needs is another problem ... but life is about to deal Stewart Gardener a whole new deck of cards when the next child to go missing is his own...

Impurity of Blood analyzes the proposition of Spanish racial thought in the late 19th and early 20th centuries that racial strength came from a fusion of different groups, rather than from a kind of racial purity. By providing a history of ethnic thought in Spain in the medieval and early modern era, and by studying the formation of racial thought in Spain's nascent human sciences and its political and cultural manifestations leading into the Franco regime, it provides a new view of racial thought in Europe and its connections to the larger twentieth century formation of racial thought in the West.

Recent regulations on heavy metal testing have required the pharmaceutical industry to monitor a suite of elemental impurities in pharmaceutical raw materials, drug products and dietary supplements. These new directives s are described in the new United States Pharmacopeia (USP) Chapters , , and , together with Q3D, Step 4 guidelines for elemental impurities, drafted by the ICH (International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use), a consortium of global pharmaceutical associations, including the European Pharmacopeia (Ph.Eur.), the Japanese Pharmacopeia (JP) and the USP. This book provides a complete guide to the analytical methodology, instrumental techniques and sample preparation procedures used for measuring elemental impurities in pharmaceutical and nutraceutical materials. It offers readers the tools to better understand plasma spectrochemistry to optimize detection capability for the full suite of elemental PDE (Permitted Daily Exposure) levels in the various drug delivery categories. Other relevant information covered in the book includes: The complete guide to measuring elemental impurities in pharmaceutical and nutraceutical materials. Covers heavy metals testing in the pharmaceutical industry from an historical perspective. Gives an overview of current USP Chapters and and ICH Q3D Step 4 Guidelines. Explains the purpose of validation protocols used in Chapter , including how J-values are calculated Describes fundamental principles and practical capabilities of ICP-MS and ICP-OES. Offers guidelines about the optimum strategy for risk assessment Provides tips on how best to prepare and present your data for regulatory inspection. An indispensable resource, the fundamental principles and practical benefits of ICP-OES and ICP-MS are covered in a reader-friendly format that a novice, who is carrying out elemental impurities testing in the pharmaceutical and nutraceutical communities, will find easy to understand.

A key component of the overall quality of a pharmaceutical is control of impurities, as their presence, even in small amounts, may affect drug safety and efficacy. The identification and quantification of impurities to acceptable standards presents a significant challenge to the analytical chemist. Analytical science is developing rapidly and provides increasing opportunity to identify the structure, and therefore the origin and safety implications of these impurities, and the challenges of their measurement drives the development of modern quantitative methods. Written for both practicing and student analytical chemists, Analysis of Drug Impurities provides a detailed overview of the challenges and the techniques available to permit accurate identification and quantification of drug impurities.

Provides a state-of-the-art account of the various effects of impurities on the properties of engineering alloys. Outlines a wide range of methods for producing cleaner alloys. Traces the technological advances that allow the economical manufacture of purer materials.