Since the turn of the century, certain parasitic diseases of livestock have frus trated efforts to bring them under control by vaccination techniques; East Coast fever and trypanosomiasis are two such diseases. East Coast fever (ECF) kills a half million cattle annually; and 3 million are killed each year by trypanosomia sis, which is widely spread over tropical Mrica. Together, these diseases have closed some 7 million square kilometers of land to livestock grazing-land that might otherwise support an additional 120 million head of cattle. In 1970 W.A. Malmquist of the U.S. Department of Agriculture, in collabora tion with K.N. Brown, M.P. Cunningham, and other associates at the East African Veterinary Research Organization in Kenya, succeeded in cultivating in vitro the protozoal organisms responsible for East Coast fever. This success, obtained utilizing tissue cultures, encouraged a number of organizations to support research on these parasites in an accelerated effort to develop field vaccines.

Since the turn of the century, certain parasitic diseases of livestock have frus trated efforts to bring them under control by vaccination techniques; East Coast fever and trypanosomiasis are two such diseases. East Coast fever (ECF) kills a half million cattle annually; and 3 million are killed each year by trypanosomia sis, which is widely spread over tropical Mrica. Together, these diseases have closed some 7 million square kilometers of land to livestock grazing-land that might otherwise support an additional 120 million head of cattle. In 1970 W.A. Malmquist of the U.S. Department of Agriculture, in collabora tion with K.N. Brown, M.P. Cunningham, and other associates at the East African Veterinary Research Organization in Kenya, succeeded in cultivating in vitro the protozoal organisms responsible for East Coast fever. This success, obtained utilizing tissue cultures, encouraged a number of organizations to support research on these parasites in an accelerated effort to develop field vaccines.

Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Examines parasites that cause malaria, babesiosis, trypanosomiasis, leishmaniasis, toxoplasmosis, pneumocytosis and filariasis.