This concise handbook provides oncologists and other healthcare providers with crucial updates in the field, including an updated review of the current understanding of the biology of the HER2 pathway, an overview of HER2-testing, and evidence-based discussions of available and emerging HER2-targeted treatment options. An essential clinical text for physicians that screen and treat patients with breast cancer and require an accessible, up-to-date survey of the dynamic treatment landscape.

Recent developments with novel systemic drugs, palliative surgical techniques and diagnostic imaging have given hope for the treatment of patients whose breast cancer has spread beyond its primary tumour. Written by a team from leading cancer centers in Europe, including the UK's Royal Marsden Hospital, the Handbook of Metastatic Breast Cancer, Sec

For trainee and practising paediatricians, this book serves as a guide to the investigations of health problems in babies and children, including a choice of investigations and tests, interpretation of results, and strategies for referral. Features include: a format organized by body system and by specific problems, for easy access; emphasis on avoiding over-investigation while providing the best and most up-to-date care; and coverage of the full range of problems arising in childhood.

In this book, the authors present current research in the study of non-small cell lung cancer. Topics discussed include the preclinical and clinical advances of epigenetics in lung cancer; therapeutic antibodies and non-coding RNAs (ncRNAs) in non-small cell lung cancer; molecular profiling in lung cancer specimens leads to targeted therapeutic options in patients with non-small cell lung carcinoma; the role of radiation dose escalation in the treatment of stage III locally advanced inoperable non-small cell lung cancer; and mechanisms of resistance to EGFR inhibitors.

Cisplatin is a platinum-based anticancer drug and widely used for the treatment of human testicular, ovarian, bladder, cervical, head and neck, and small cell lung cancers. Its anticancer activity results from the modification of DNA through covalent cross-linkings or platinum (Pt)-DNA adducts. This book presents topical research in the study of the pharmacology, clinical uses and adverse effects of cisplatin therapy.