Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.

This book examines protist-, animal- or plant-bacterial interactions and symbioses. These symbioses rely on continuous cell-to-cell communications. The goals of this book are to explore, explain and expose these dialogues across a broad spectrum of plant and animal eukaryotes to a broad field of biologists.

The Proceedings of the 19th International Seaweed Symposium provides an invaluable reference to a wide range of fields in applied phycology. Papers cover topics as diverse as the systematics, ecology, physiology, integrated multitrophic aquaculture, commercial applications, carbohydrate chemistry and applications, harvesting biology, cultivation of seaweeds and microalgae and more. Contributions from all parts of the world give the volume exceptional relevance in an increasingly global scientific and commercial climate. Like its predecessors, this volume provides a benchmark of progress in all fields of applied seaweed science and management, and will be referred to for many years to come.

These original contributions by symbiosis biologists and evolutionary theorists address the adequacy of the prevailing neo-Darwinian concept of evolution in the light of growing evidence that hereditary symbiosis, supplemented by the gradual accumulation of heritable mutation, results in the origin of new species and morphological novelty.A departure from mainstream biology, the idea of symbiosis--as in the genetic and metabolic interactions of the bacterial communities that became the earliest eukaryotes and eventually evolved into plants and animals--has attracted the attention of a growing number of scientists.These original contributions by symbiosis biologists and evolutionary theorists address the adequacy of the prevailing neo-Darwinian concept of evolution in the light of growing evidence that hereditary symbiosis, supplemented by the gradual accumulation of heritable mutation, results in the origin of new species and morphological novelty. They include reports of current research on the evolutionary consequences of symbiosis, the protracted physical association between organisms of different species. Among the issues considered are individuality and evolution, microbial symbioses, animal-bacterial symbioses, and the importance of symbiosis in cell evolution, ecology, and morphogenesis. Lynn Margulis, Distinguished Professor of Botany at the University of Massachusetts at Amherst, is the modern originator of the symbiotic theory of cell evolution. Once considered heresy, her ideas are now part of the microbiological revolution. ContributorsPeter Atsatt, Richard C. Back, David Bermudes, Paola Bonfante-Fasolo, René Fester, Lynda J. Goff, Anne-Marie Grenier, Ricardo Guerrero, Robert H. Haynes, Rosmarie Honegger, Gregory Hinkle, Kwang W. Jeon, Bryce Kendrick, Richard Law, David Lewis, Lynn Margulis, John Maynard Smith, Margaret J. McFall-Ngai, Paul Nardon, Kenneth H. Nealson, Kris Pirozynski, Peter W. Price, Mary Beth Saffo, Jan Sapp, Silvano Scannerini, Werner Schwemmler, Sorin Sonea, Toomas H. Tiivel, Robert K. Trench, Russell Vetter

Microbiota are a promising and fascinating subject in biology because they integrate the microbial communities in humans, animals, plants, and the environment. In humans, microbiota are associated with the gut, skin, and genital, oral, and respiratory organs. The plant microbial community is referred to as "holobiont," and it is influential in the maintenance and health of plants, which themselves play a role in animal health and the environment. The contents of Microbiome-Host Interactions cover all areas as well as new research trends in the fields of plant, animal, human, and environmental microbiome interactions. The book covers microbiota in polar soil environments, in health and disease, in Caenorhabditis elegans, and in agroecosystems, as well as in rice root and actinorhizal root nodules, speleothems, and marine shallow-water hydrothermal vents. Moreover, this book provides comprehensive accounts of advanced next-generation DNA sequencing, metagenomic techniques, high-throughput 16S rRNA sequencing, and understanding nucleic acid sequence data from fungal, algal, viral, bacterial, cyanobacterial, actinobacterial, and archaeal communities using QIIME software (Quantitative Insights into Microbial Ecology). FEATURES Summarizes recent insight in microbiota and host interactions in distinct habitats, including Antarctic, hydrothermal vents, speleothems, oral, skin, gut, feces, reproductive tract, soil, root, root nodules, forests, and mangroves Illustrates the high-throughput amplicon sequencing, computational techniques involved in the microbiota analysis, downstream analysis and visualization, and multivariate analysis commonly used for microbiome analysis Describes probiotics and prebiotics in the composition of the gut microbiota, skin microbiome impact in dermatologic disease prevention, and microbial communities in the reproductive tract of humans and animals Presents information in a reachable way for students, teachers, researchers, microbiologists, computational biologists, and other professionals who are interested in strengthening or enlarging their knowledge about microbiome analysis with next-generation DNA sequencing in the different branches of the sciences

The most up-to-date reference on phytomicrobiomes available today The Plant Microbiome in Sustainable Agriculture combines the most relevant and timely information available today in the fields of nutrient and food security. With a particular emphasis on current research progress and perspectives of future development in the area, The Plant Microbiome in Sustainable Agriculture is an invaluable reference for students and researchers in the field, as well as those with an interest in microbiome research and development. The book covers both terrestrial and crop associated microbiomes, unveiling the biological, biotechnological and technical aspects of research. Topics discussed include: Developing model plant microbiome systems for various agriculturally important crops Defining core microbiomes and metagenomes in these model systems Defining synthetic microbiomes for a sustainable increase in food production and quality The Plant Microbiome in Sustainable Agriculture is written to allow a relative neophyte to learn and understand the basic concepts involved in phytomicrobiomes and discuss them intelligently with colleagues.