Provides advice to Henry Jackson Knox as to how best to arrange financial matters, such as the family business, to provide for the Knox family after the death of Henry Knox. Mentions the possible effects of the European war on pursuing mercantile interests.

Discusses the proper time to sell goods recently arrived from London that were consigned to Henry Knox. Relates that Granville Sharp sent a box of books intended for Knox, Harvard College, Rhode Island College, and George Washington. The books were damaged in transit, and are presently with Lucy, Knox's wife. Reports that in a recent meeting (held at Faneuil Hall in Boston) merchants resolved to have no dealings whatever with any British mercht. agents... that we will not receive them to Board-Speak or have any connections with them, [that] we will not Let them a House shop-store, or Wharfe... In consequence, the British merchants are leaving Boston. Reports that Lucy's sister Hannah recently informed Lucy of the death of their brother.

Notes he received Knox's post and is all anxiety to learn that you have fin'd the business with Mr. B [William Bingham?] - and also concluded with Mr [William] Duer... Informs Knox that he has sent all of the copies out and that [Jean-Baptiste] de la Roche has left for the Eastern Lands in a very good mood. Free stamped on address leaf with no signature.

Writes that he has received Knox's recent letters, and assures him he will try to help Knox in whatever way possible. Adds that he does not lack the will to help, but does lack the means. Declares that he was unable to avoid paying some of Knox's interest, but will try to avoid paying more interest if he can. Discusses helping Knox with obtaining supplies for a ship. Mentions financial arrangements with several people, including Samuel Waldo. Also reports the death of an acquaintance, Mrs. Geyer.

Signed twice by Jackson. References Knox's letter of 20 March. Has heard nothing from William Tudor since the last letter he forwarded to Knox. Relates that his note to Tudor was due 17 March. Reports that [Thomas?] Adams the printer informed him that the article in a North Carolina newspaper Knox was asking about was inclosed to him by a Gentleman from Pensylvania. Adams would not give the gentleman's name, nor confirm it came from Philadelphia. Jackson believes he can find out the name if Knox wishes to know. Refers Knox to William Bingham's letter about their land concern. Wants to go to Maine with Knox, and reminds him they are embarking from Portland now as a packet now runs regularly between there and Boston. Says I am anxious for your present situation but hope & pray for the best, you will let me know when all danger is over, that my mind may be releived from its present fears & apprehensions. Says he intends to visit a Public Exhibition of the Students at the Hingham Academy. Will see Henry Jackson Knox there who Henry Jackson refers to as my boy. Reports that the boy needs steadiness, but that he has improved upon his language, manners & deportment. Speaks highly of the boy and hopes he will continue where he is until he enters Harvard. Is very much against the boy going home for the summer. Continues letter on 1 April. Encloses correspondence he has had with Judge Sullivan. This will show Knox the situation they are in since they have not made the [Dollar sign]30,000 payment as their contract stipulates. Hopes Knox will consult Bingham on the subject. Reminds him the [Dollar sign]5,200 note is due 29 April.

Reports that he has written to a Mr. Sumner to ask for men to work at his business, and also for mattresses and blankets for them to use. Discusses developments with his lime works, such as the construction of kilns. Asks Knox to send several barrels of pork and beef so he can feed his workers.