Three of every four children and adolescents with cancer can now be cured. However, physicians are using increasingly intensive treatment regimens. These treatments can expose patients to toxic chemotherapeutic agents, invasive surgical procedures, and radiation oncology interventions that risk disfigurement, neuropsychiatric damage, and life-threatening organ toxicity. These potentially dire consequences have mandated that advances in cancer treatment go hand in hand with supportive care measures that sustain patients through their therapeutic ordeal and allow each patient to achieve maximum quality of life. In this book, now in its third edition, the discipline of supportive care in pediatric oncology is covered in depth. Supportive Care of Children with Cancer is a ready-reference handbook designed for use at the hospital bedside, in the oncology outpatient clinic, or in the physician's office. To create this book, leading experts in the field recommended approaches to supportive care which were then critically reviewed by members of the Children's Oncology Group, the world's largest cooperative study group for children's cancer. For students, house officers, fellows, pediatric oncologists, surgeons, nurses, nutritionists, social workers, and psychologists, this book provides essential information about the care of pediatric oncology patients. The third edition features a new chapter on recognition, prevention, and remediation of burnout in pediatric oncology staff members, while throughout the book, chapters have been revised and updated to reflect the impact of new antibiotic agents, new antiemetics, and new approaches to pain management.

This new edition of Handbook of Pediatric Hematology and Oncology: Children's Hospital & Research Center Oakland features practical guidance on how to handle common inpatient and outpatient challenges seen in pediatric hematology and oncology. Designed as a rapid reference to the latest diagnostic and therapeutic protocols, the text is short and didactic and supplemented with practical algorithms and case studies throughout. Completely revised and updated, there are brand-new chapters on subjects including bone marrow transplantation, pain management and palliative care. Comprehensive, yet concise, the handbook presents essential guidelines on the diagnosis and management of the most common pediatric blood disorders and malignancies, in addition to chemotherapeutic drug information and transfusion protocols. Designed for medical students, residents, and fellows, this user-friendly portable reference is also the perfect companion on the ward for pediatric hematology and oncology nurses.

This volume provides a comprehensive overview of critical care of the pediatric immunocompromised hematology-oncology patient. The text focuses on unique aspects of the pediatric immunocompromised patient that predisposes the child to significant illness, and presents critical care management strategies specific to the patient population. In addition to chapters on oncology, primary immune deficiency, immunocompromised hematology, and hematopoietic cell transplant patients, the book covers the changing landscape of ICU care, pharmacologic considerations, and psychological and social aspects of the critical care of hematology-oncology patients. Written by experts from a range of disciplines, Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient: An Evidence-Based Guide is a valuable resource for clinicians and practitioners who treat this patient population.

Pediatric Oncology Nursing: Advanced Clinical Hand- signs, diagnostic and laboratory procedures, tre- book is a joint effort between nurses in Canada, the ment, prognosis, and follow up care are included for United Kingdom, and the United States. This is the each of the disorders. second edition, and has been another wonderful Part III covers cancer treatment, including c- opportunity to bring together the expertise of hema- motherapy, radiation therapy, hematopoetic stem cell tology and oncology nurses from two continents. The transplantation, surgery, gene therapy, biotherapy, c- book is designed to be a comprehensive clinical hand- plimentary and alternative medicine, and clinical trials. book for nurses in advanced practice working with The principles and description of treatment, method pediatric hematology/oncology patients. Speci? c of treatment delivery, potential side effects, and special issues related to young children and adolescents with considerations for each type of treatment are discussed. cancer and hematologic disorders are discussed. Part IV focuses on the side effects of cancer Thirty-one contributors and two editors partici- treatment in relation to metabolic processes and pated in the writing of this text. Individuals in advanced gastrointestinal, hematologic, respiratory, renal, c- practice and academic roles – nurse practitioners, clin- diovascular, neurologic, musculoskeletal, integum- ical nurse specialists, nutritionists, clinical instructors, tary, endocrine, and auditory systems. The incidence, lecturers, academicians, and educators – were involved. etiology, treatment, prevention, and prognosis are One of the most appealing features of this text is the included for each side effect reviewed.

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Der überarbeitete Leitfaden für Diagnose, Management und Behandlung von Blutkrankheiten und Krebs bei Kindern. Kinder mit Blutkrankheiten und Krebs sind eine ganz spezifische Gruppe, die besondere Diagnosemaßnahmen und ein spezifisches Management erfordert. Das Handbook of Pediatric Hematology and Oncology stellt Klinikern auf jedem Niveau anhand eines aktuellen Algorithmus praxisorientierte Handlungsanleitungen zur Verfügung. Die aktualisierte dritte Auflage wurde von einem Expertenteam des Children`s Hospital & Research Center Oakland zusammengestellt. - Präsentiert aktuelle Management- und Behandlungsrichtlinien für die meisten bekannten Blutkrankheiten und bösartigen Krebserkrankungen. - Neuester Algorithmus-Ansatz für Diagnose und Management der häufigsten Krankheitsbilder mit Verweisen zur Fachliteratur. - Bietet zum schnellen Nachschlagen Tabellen mit visualisierten Darstellungen der Symptome, Laborergebnissen, Differenzialdiagnosen und beinhaltet Behandlungsempfehlungen. - Zeigt mittels Fallstudien die verschiedenen hämatologischen und onkologischen Aspekte, u. a. hämolytische Anämie, Sichelzellenkrankheit, Hämophilie, Neuroblastom, weiches und hartes Sarkom. -Enthält eine nützliche Arzneimittelliste und Informationen zu chemotherapeutischen Wirkstoffen, Dosierung, Handlungsmechanismen, Schwangerschaft, Indikationen und Nebenwirkungen. - Behandelt Transfusionsmedizin, Stammzellentransplantation, Management zentraler Venenkatheter, Schmerzbehandlung, onkologische Notfälle und Grundlagen der Chemotherapie. Aufgrund seiner Praxisorientierung und des handlichen Formats ist die 3. Auflage des Handbook of Pediatric Hematology and Oncology eine unschätzbare Quelle für Medizinstudenten, Praktikanten, Patienten, Fach- und Pflegepersonal in der pädiatrischen Hämatologie und Onkologie, Kinderärzte und Einsteiger in das Fachgebiet der Hämatologie und Onkologie.