This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.

“Easily the best baseball book ever produced by anyone.” —Cleveland Plain Dealer “This was the best baseball book published in 1966, it is the best baseball book of its kind now, and, if it is reissued in 10 years, it will be the best baseball book.” — People From Lawrence Ritter, co-author of The Image of Their Greatness and The 100 Greatest Baseball Players of All Time, comes one of the bestselling, most acclaimed sports books of all time. Baseball was different in earlier days—tougher, more raw, more intimate—when giants like Babe Ruth and Ty Cobb ran the bases. In the monumental classic The Glory of Their Times, the golden era of our national pastime comes alive through the vibrant words of those who played and lived the game. It is a book every baseball fan should read!

This report focuses on preventing potentially disabling conditions from developing into disabilities and on minimizing the effects of such conditions on a person's productivity and quality of life. It describes disability as a social and public health issue and not just a physical condition. The report begins with an executive summary, an introduction which discusses prevention issues in general and defines concepts, and a list of 27 recommendations. Subsequent chapters discuss: (1) the magnitude and dimensions of disability in the United States; (2) a conceptual approach to disability prevention and use of the tools and principles of epidemiology; (3) major areas of disability (developmental disabilities, injury-related disabilities, chronic diseases and aging, and secondary conditions associated with primary disabling conditions); (4) government and private sector programs concerned with disability prevention; and (5) conclusions and recommendations in the areas of a national program for the prevention of disability, surveillance, research, access to care and preventive services, and professional and public education. Appendixes contain a paper by Saad Z. Nagi titled "Disability Concepts Revisited: Implications for Prevention"; a statement of one committee member dissenting from this majority report of the Committee on a National Agenda for the Prevention of Disabilities; a response to the dissenting statement by committee members; and committee biographies. (Approximately 375 references) (JDD)

This title will be available in a looseleaf format for spring 2023 use. The casebound book will be published later in the spring. The second edition of Internet and Telecommunications Regulation has been completely revised, with the authors adding large sections that place the regulation of internet services at the heart of the book. The text is organized around regulatory themes, including the use of antitrust and sector-specific laws to respond to concerns about competition; the constraints on regulation imposed by the First Amendment; the relationship between state, national, and international regulation; the role of copyright; and statutory immunity for platforms from civil liability for third-party content. The book also includes important materials on the regulation of traditional telecommunications services not only because those services are important in their own right but also because the regulation of internet services builds on the regulation of traditional telecommunications services. Internet and Telecommunications Regulation contains discussions and excerpts from legal materials to help readers understand current controversies, regulatory strategies, and the historical developments that led to them. Summaries and previews at the start of each set of readings help students understand the relevance of the readings and the larger issues they present, and questions at the end of each excerpt encourage students to think critically about those materials. The organization easily permits the selection of material for courses focused on particular industries or on particular types of regulation.

History of pastor's ministry in one place.