"This is the colorful and dramatic biography of two of America's most controversial entrepreneurs: Moses Louis Annenberg, 'the racing wire king, ' who built his fortune in racketeering, invested it in publishing, and lost much of it in the biggest tax evasion case in United States history; and his son, Walter, launcher of TV Guide and Seventeen magazines and former ambassador to Great Britain."--Jacket.

This book brings together the most important insights from the vast amount of literature on the origin of language.

Personalized medicine employing patient-based tailor-made therapeutic drugs is taking over treatment paradigms in a variety of ?elds in oncology and the central nervous system. The success of such therapies is mainly dependent on ef?cacious therapeutic drugs and a selective imaging probe for identi?cation of potential responders as well as therapy monitoring for an early bene?t assessment. Molecular imaging (MI) is based on the selective and speci?c interaction of a molecular probe with a biological target which is visualized through nuclear, magnetic resonance, near infrared or other methods. Therefore it is the method of choice for patient selection and therapy monitoring as well as for speci?c e- point monitoring in modern drug development. PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry. ‘PET chemistry’ can be de?ned as the study of positron-emitting compounds regarding their synthesis, structure, composition, reactivity, nuclear properties and processes and their properties in natural and - natural environments. In practice PET chemistry is strongly in?uenced by the unique properties of the radioisotopes used (e. g. , half-life, che- cal reactivity, etc. ) and integrates scienti?c aspects of nuclear-, organic-, inorganic- and biochemistry.

This fully updated Second Edition focuses sharply on clinical PET-CT and SPECT-CT examinations, omitting lengthy physics discussions. The book is now strictly disease oriented and integrates PET-CT and SPECT-CT applications completely. When both techniques are relevant for a disease, they are discussed together; when only one is relevant, it is discussed alone. More than 1,200 illustrations are included. A bound-in DVD contains over 80 cases to be viewed in three orthogonal planes and different CT windows organized as reference and self-assessment files. The cases provide excellent training and allow readers to test their abilities in making diagnoses on their own.

This annual update reports on developments in the global HIV/AIDS epidemic and draws on the most recent data available to give global and regional estimates of its scope and human toll. This edition also includes a special section on women and AIDS. Findings for 2004 include: the total number of people living with HIV reached its highest ever level of an estimated 39.4 million, with numbers rising in every region; 4.9 million new cases during the year and an estimated 3.1 million deaths; globally, just under half of all people living with HIV are women, with the proportion continuing to rise in most regions, particularly in Eastern Europe, Asia and Latin America.

Shortwave broadcasting originated in the 1920s, when stations used the new technology to increase their range in order to serve foreign audiences and reach parts of their own country not easily otherwise covered. The early days of shortwave radio were covered in On the Short Waves, 1923-1945: Broadcast Listening in the Pioneer Days of Radio, published by McFarland in 1999 (paperback 2007). Then, two companion volumes were published, picking up the story after World War II. They were Listening on the Short Waves, 1945 to Today (McFarland, 2008; paperback 2010), which focuses on the shortwave listening community, and the present Broadcasting title, about the stations themselves and their environment. The heart of the book is a detailed, year-by-year account of the shortwave bands in each year from 1945 to 2008. It reviews what American listeners were hearing on the international and domestic shortwave bands, describes the arrivals and departures of stations, and recounts important events. The book describes the several categories of broadcasters--international, domestic, private, religious, clandestine and pirate. It explains the impact of relay stations, frequency management, and jamming. It also addresses the considerable changes in shortwave broadcasting since the end of the Cold War. The book is richly illustrated and indexed, and features a bibliography and extensive notes.