The Middle East plays a major role in the history of genetic science. Early in the twentieth century, technological breakthroughs in human genetics coincided with the birth of modern Middle Eastern nation-states, who proclaimed that the region's ancient history—as a cradle of civilizations and crossroads of humankind—was preserved in the bones and blood of their citizens. Using letters and publications from the 1920s to the present, Elise K. Burton follows the field expeditions and hospital surveys that scrutinized the bodies of tribal nomads and religious minorities. These studies, geneticists claim, not only detect the living descendants of biblical civilizations but also reveal the deeper past of human evolution. Genetic Crossroads is an unprecedented history of human genetics in the Middle East, from its roots in colonial anthropology and medicine to recent genome sequencing projects. It illuminates how scientists from Turkey to Yemen, Egypt to Iran, transformed genetic data into territorial claims and national origin myths. Burton shows why such nationalist appropriations of genetics are not local or temporary aberrations, but rather the enduring foundations of international scientific interest in Middle Eastern populations to this day.

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students. As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource. - Provides practical analysis of the ethical issues raised by cutting-edge techniques and recent advances in prenatal and reproductive genetics - Contains contributions from leading bioethicists and clinicians who offer a global, holistic perspective on applied challenges and moral questions relating to genetic and genomic reproductive technology - Discusses preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, ethical issues, and more

Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. - Takes an integrated approach to infectious diseases - Provides the latest developments in the field of infectious diseases - Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases - Includes updated and revised contributions from leading authorities, along with six new chapters

Sociogenomics has rapidly become one of the trendiest sciences of the new millennium. Practitioners view human nature and life outcomes as the result of genetic and social factors. In Social by Nature, Catherine Bliss recognizes the promise of this interdisciplinary young science, but also questions its implications for the future. As she points out, the claim that genetic similarities cause groups of people to behave in similar ways is not new—and a dark history of eugenics warns us of its dangers. Over the last decade, sociogenomics has enjoyed a largely uncritical rise to prominence and acceptance in popular culture. Researchers have published studies showing that things like educational attainment, gang membership, and life satisfaction are encoded in our DNA long before we say our first word. Strangely, unlike the racial debates over IQ scores in the '70s and '90s, sociogenomics has not received any major backlash. By exposing the shocking parallels between sociogenomics and older, long-discredited, sciences, Bliss persuasively argues for a more thoughtful public reception of any study that reduces human nature to a mere sequence of genes. This book is a powerful call for researchers to approach their work in more socially responsible ways, and a must-read for anyone who wants to better understand the scholarship that impacts how we see ourselves and our society.

Over the past forty years, the criminal justice system in the United States has engaged in a very expensive policy failure, attempting to punish its way to public safety, with dismal results. So-called "tough on crime" policies have not only failed to effectively reduce crime, recidivism, and victimization but also created an incredibly inefficient system that routinely fails the public, taxpayers, crime victims, criminal offenders, their families, and their communities. Strategies that focus on behavior change are much more productive and cost effective for reducing crime than punishment, and in this book, William R. Kelly discusses the policy, process, and funding innovations and priorities that the United States needs to effectively reduce crime, recidivism, victimization, and cost. He recommends proactive, evidence-based interventions to address criminogenic behavior; collaborative decision making from a variety of professions and disciplines; and a focus on innovative alternatives to incarceration, such as problem-solving courts and probation. Students, professionals, and policy makers alike will find in this comprehensive text a bracing discussion of how our criminal justice system became broken and the best strategies by which to fix it.

This fourth volume in the Handbook of Stress series, Stress: Genetics, Epigenetics and Genomics, deals with the influence that genetics, epigenetics, and genomics have on the effects of and responses to stress. Chapters refer to epigenetic mechanisms that involve DNA methylation, histone modification, and/or noncoding RNA-associated gene activation or silencing. There is also coverage of epigenetic mechanisms in stress-related transgenerational transmission of characteristics, and how these may help explain heritability in some complex human diseases.The Handbook of Stress series, comprised of self-contained volumes that each focus on a specific stress area, covers the significant advances made since the publication of Elsevier's Encyclopedia of Stress (2000 and 2007). Volume 4 is ideal for graduate students, post-doctoral fellows, faculty and clinicians interested in stress genetics, epigenetics and genomics involved in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry and the social sciences - Articles carefully selected by eminent stress researchers and prepared by contributors representing outstanding scholarship in the field, with each chapter fully vetted for reliable expert knowledge - Richly illustrated with explanatory figures and tables - Each chapter includes a boxed "Key points call out section - Affordably priced, self-contained volume for readers specifically interested in stress genetics and epigenetics, removing the need to purchase the whole Handbook series