Hippocrates is a towering figure in Greek medicine. Dubbed the 'father of medicine', he has inspired generations of physicians over millennia in both the East and West. Despite this, little is known about him, and scholars have long debated his relationship to the works attributed to him in the so-called 'Hippocratic Corpus', although it is undisputed that many of the works within it represent milestones in the development of Western medicine. In this Companion, an international team of authors introduces major themes in Hippocratic studies, ranging from textual criticism and the 'Hippocratic question' to problems such as aetiology, physiology and nosology. Emphasis is given to the afterlife of Hippocrates from Late Antiquity to the modern period. Hippocrates had as much relevance in the fifth-century BC Greek world as in the medieval Islamic world, and he remains with us today in both medical and non-medical contexts.

In Galen's Theory of Black Bile: Hippocratic Tradition, Manipulation, Innovation Keith Stewart analyses Galen's characterisation of black bile to understand the different ways it is used in his arguments that cannot always be reconciled with the content of his sources.

Galen of Pergamon, was a prominent Roman physician, surgeon and philosopher. The most accomplished of all medical researchers of antiquity, Galen contributed greatly to the understanding of numerous scientific disciplines, including anatomy, physiology, pathology, pharmacology, and neurology, as well as philosophy and logic. Galen's understanding of anatomy and medicine was principally influenced by the then current theory of humorism, as advanced by many ancient Greek physicians such as Hippocrates. His theories dominated and influenced Western medical science for more than 1,300 years. Medical students continued to study Galen's writings until well into the 19th century. Galen conducted many nerve ligation experiments that supported the theory, which is still accepted today that the brain controls all the motions of the muscles by means of the cranial and peripheral nervous systems.

Mixtures is of central importance for Galen's views on the human body. It presents his influential typology of the human organism according to nine mixtures (or 'temperaments') of hot, cold, dry and wet. It also develops Galen's ideal of the 'well-tempered' person, whose perfect balance ensures excellent performance both physically and psychologically. Mixtures teaches the aspiring doctor how to assess the patient's mixture by training one's sense of touch and by a sophisticated use of diagnostic indicators. It presents a therapeutic regime based on the interaction between foods, drinks, drugs and the body's mixture. Mixtures is a work of natural philosophy as well as medicine. It acknowledges Aristotle's profound influence whilst engaging with Hippocratic ideas on health and nutrition, and with Stoic, Pneumatist and Peripatetic physics. It appears here in a new translation, with generous annotation, introduction and glossaries elucidating the argument and setting the work in its intellectual context.

In Galen’s Theory of Black Bile: Hippocratic Tradition, Manipulation, Innovation Keith Stewart investigates Galen’s writing on black bile to explain health and disease and shows that Galen sometimes presented this humour as three substances with different properties that can either be harmful or beneficial to the body. Keith Stewart analyses the most important treatises for Galen’s physical description and characteristion of black bile and challenges certain views on the development of this humour, such as the importance of the content of the Hippocratic On the Nature of Man. This analysis allows us to understand how and why Galen defines and uses black bile in different ways for his arguments that cannot always be reconciled with the content of his sources.