he history of chemistry is a story of human endeavor-and as er T ratic as human nature itself. Progress has been made in fits and starts, and it has come from all parts of the globe. Because the scope of this history is considerable (some 100,000 years), it is necessary to impose some order, and we have organized the text around three dis cemible-albeit gross--divisions of time: Part 1 (Chaps. 1-7) covers 100,000 BeE (Before Common Era) to the late 1700s and presents the background of the Chemical Revolution; Part 2 (Chaps. 8-14) covers the late 1700s to World War land presents the Chemical Revolution and its consequences; Part 3 (Chaps. 15-20) covers World War I to 1950 and presents the Quantum Revolution and its consequences and hints at revolutions to come. There have always been two tributaries to the chemical stream: experiment and theory. But systematic experimental methods were not routinely employed until the 1600s-and quantitative theories did not evolve until the 1700s-and it can be argued that modem chernistry as a science did not begin until the Chemical Revolution in the 1700s. xi xii PREFACE We argue however that the first experiments were performed by arti sans and the first theories proposed by philosophers-and that a rev olution can be understood only in terms of what is being revolted against.

Drawing on alchemical theory, Édouard Laugier and Auguste Laurent set out to find the vital essence of life through the craft of perfumes. While drawing the ire of enlightened Bohemian Paris, they discovered fundamental differences in the structures of naturally occurring and synthetic molecules, inaugurating a persistent scientific mystery.

From the 1770s through the 1820s the French scientific community predominated in the world to a degree that no other scientific establishment did in any period prior to the Second World War. In his classic Science and Polity in France: The End of the Old Regime, Charles Gillispie analyzed the cultural, political, and technical factors that encouraged scientific productivity on the eve of the Revolution. In the present monumental and elegantly written sequel to that work, which Princeton is reissuing concurrently, he examines how the revolutionary and Napoleonic context contributed to modernization both of politics and science. In politics, argues Gillispie, the central feature of this modernization was conversion of subjects of a monarchy into citizens of a republic in direct contact with a state enormously augmented in power. To the scientific community, attainment of professional status was what citizenship was to all Frenchmen in the republic proper, namely the license to self-governance and dignity within the respective contexts. Revolutionary circumstances set up a resonance between politics and science since practitioners of both were future oriented in their outlook and scornful of the past. Among the creations of the First French Republic were institutions providing the earliest higher education in science. From them emerged rigorously trained people who constituted the founding generation in the disciplines of mathematical physics, positivistic biology, and clinical medicine. That scientists were able to achieve their ends was owing to the expertise they provided the revolutionary and imperial authorities in education, medicine, warfare, empire building, and industrial technology.