International Reviews of Child Neurology Series No. 13 Given the tremendous advances in the last five years in the understanding of acquired neonatal brain injury and in the care of affected newborn infants, this book provides a timely review for the practising neurologist, neonatologist and pediatrician. The editors take a pragmatic approach, focusing on specific populations encountered regularly by the clinician. They begin by addressing aspects of fetal neurology and the interpretation of fetal imaging studies. They then follow a “bench to bedside” approach to acquired brain injury in the preterm and term newborn infant in the next chapters. The contributors, all internationally recognized clinician scientists, provide the clinician reader with a state-of-the art review in their area of expertise. The final section of the book address special populations and concerns, areas that are largely overlooked in existing neurology textbooks. Each of these areas has seen considerable advances in the last five years and is of increasing relevance to the neurologist and neonatologist clinician. The comprehensive nature of each section (from basic science to acute clinical care to outcomes) should appeal broadly to scientists and allied health professionals working in neonatal neurology. Readership Paediatric neurologists, neonatologists, neurologists and paediatricians, clinicians in child development, child health researchers and allied health professionals (in physiotherapy, occupational therapy, speech therapy and psychology). Trainees in these areas.

Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.

Now in its third edition, this is a comprehensive survey of fetal and neonatal brain injury arising from hypoxia, ischemia or other causes. The volume spans a broad range of areas from epidemiology and pathogenesis, through to clinical manifestations and obstetric care, and then on to diagnosis, long-term outcomes, and medico-legal aspects. An important theme running throughout is to highlight scientific and clinical advances that have a role to play in minimising risk, improving clinical care and outcomes.

MRI OF THE NEONATAL BRAIN, 4TH EDITION provides a comprehensive and integrated approach to the role of magnetic resonance imaging (MRI) of the brain in neonatology. MRI is becoming increasingly available to clinicians and has been shown to have major advantages over ultrasound as an aid to diagnosis. MRI OF THE NEONATAL BRAIN, 4TH EDITION is divided into four major parts. Part I covers the technical aspects, explaining how MRI works and advising on how to achieve the best possible image with minimal sedation of the neonate. Part II illustrates the normal anatomy and development of the neonatal brain. Part III is a short section on the pathological processes underlying brain disorders in the neonate. Part IV, the largest section of the book, discusses the most common disorders seen in the newborn infant, and contains a series of case studies with discussions, questions and answers.

Development of the brain and the emergence of the mind constitute some of the most important concerns of contemporary biology. Disturbances during fetal life may have profound implications for a child's future neurological and psychological development, which can in turn impact society. The new edition of this highly respected work presents a comprehensive review of the basic mechanisms of brain development and the pathophysiology of disorders of the infant brain, written by a team of distinguished neuroscientists, neonatologists, and neuropediatricians. The book follows the main milestones of brain development, from formation of the neural tube and wiring of the neurons in the brain. Neurotrophic factors, neurotransmitters, glial cell biology, cerebral circulation development of sensory functions are all described in detail. Furthermore, there are more philosophical chapters on the evolution of the brain and the emergence of consciousness. Clinical considerations are highlighted where relevant.

This book clearly explains the basics of cranial ultrasonography in the neonate, from patient preparation through to screening strategies and the classification of abnormalities. The aim is to enable the reader consistently to obtain images of the highest quality and to interpret them correctly. Essential information is provided both on the procedure itself and on the normal ultrasound anatomy. The standard technique is described and illustrated, and emphasis is placed on the value of supplementary acoustic windows. Attention is also drawn to maturational changes in the neonatal brain and to the limitations of cranial ultrasonography. Frequently occurring abnormalities are described and classifications for these abnormalities are provided. A new classification for neonatal cerebellar hemorrhages is introduced. In this third edition, all ultrasound images have beena replaced, reflecting the improvements in image quality. An entirely new chapter is devoted to Doppler ultrasonography. The illustrations have been improved and new illustrations were added. The reader will have access to highly informative videos on the cranial ultrasound procedure, available online via SpringerLink. The compact design of the book makes it an ideal and handy reference that will guide the novice in understanding the essentials of the technique while also providing useful information for the more experienced practitioner.