Exploring Modeling with Data and Differential Equations Using R provides a unique introduction to differential equations with applications to the biological and other natural sciences. Additionally, model parameterization and simulation of stochastic differential equations are explored, providing additional tools for model analysis and evaluation. This unified framework sits "at the intersection" of different mathematical subject areas, data science, statistics, and the natural sciences. The text throughout emphasizes data science workflows using the R statistical software program and the tidyverse constellation of packages. Only knowledge of calculus is needed; the text’s integrated framework is a stepping stone for further advanced study in mathematics or as a comprehensive introduction to modeling for quantitative natural scientists. The text will introduce you to: modeling with systems of differential equations and developing analytical, computational, and visual solution techniques. the R programming language, the tidyverse syntax, and developing data science workflows. qualitative techniques to analyze a system of differential equations. data assimilation techniques (simple linear regression, likelihood or cost functions, and Markov Chain, Monte Carlo Parameter Estimation) to parameterize models from data. simulating and evaluating outputs for stochastic differential equation models. An associated R package provides a framework for computation and visualization of results. It can be found here: https://cran.r-project.org/web/packages/demodelr/index.html.

Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected.

Exploring ODEs is a textbook of ordinary differential equations for advanced undergraduates, graduate students, scientists, and engineers. It is unlike other books in this field in that each concept is illustrated numerically via a few lines of Chebfun code. There are about 400 computer-generated figures in all, and Appendix B presents 100 more examples as templates for further exploration.?

This volume presents the most recent applied and methodological issues in stochastic modeling and data analysis. The contributions cover various fields such as stochastic processes and applications, data analysis methods and techniques, Bayesian methods, biostatistics, econometrics, sampling, linear and nonlinear models, networks and queues, survival analysis, and time series. The volume presents new results with potential for solving real-life problems and provides novel methods for solving these problems by analyzing the relevant data. The use of recent advances in different fields are emphasized, especially new optimization and statistical methods, data warehouse, data mining and knowledge systems, neural computing, and bioinformatics.

Speaking directly to the growing importance of research experience in undergraduate mathematics programs, this volume offers suggestions for undergraduate-appropriate research projects in mathematical and computational biology for students and their faculty mentors. The aim of each chapter is twofold: for faculty, to alleviate the challenges of identifying accessible topics and advising students through the research process; for students, to provide sufficient background, additional references, and context to excite students in these areas and to enable them to successfully undertake these problems in their research. Some of the topics discussed include: • Oscillatory behaviors present in real-world applications, from seasonal outbreaks of childhood diseases to action potentials in neurons • Simulating bacterial growth, competition, and resistance with agent-based models and laboratory experiments • Network structure and the dynamics of biological systems • Using neural networks to identify bird species from birdsong samples • Modeling fluid flow induced by the motion of pulmonary cilia Aimed at undergraduate mathematics faculty and advanced undergraduate students, this unique guide will be a valuable resource for generating fruitful research collaborations between students and faculty.

Modelling Spatial and Spatial-Temporal Data: A Bayesian Approach is aimed at statisticians and quantitative social, economic and public health students and researchers who work with spatial and spatial-temporal data. It assumes a grounding in statistical theory up to the standard linear regression model. The book compares both hierarchical and spatial econometric modelling, providing both a reference and a teaching text with exercises in each chapter. The book provides a fully Bayesian, self-contained, treatment of the underlying statistical theory, with chapters dedicated to substantive applications. The book includes WinBUGS code and R code and all datasets are available online. Part I covers fundamental issues arising when modelling spatial and spatial-temporal data. Part II focuses on modelling cross-sectional spatial data and begins by describing exploratory methods that help guide the modelling process. There are then two theoretical chapters on Bayesian models and a chapter of applications. Two chapters follow on spatial econometric modelling, one describing different models, the other substantive applications. Part III discusses modelling spatial-temporal data, first introducing models for time series data. Exploratory methods for detecting different types of space-time interaction are presented followed by two chapters on the theory of space-time separable (without space-time interaction) and inseparable (with space-time interaction) models. An applications chapter includes: the evaluation of a policy intervention; analysing the temporal dynamics of crime hotspots; chronic disease surveillance; and testing for evidence of spatial spillovers in the spread of an infectious disease. A final chapter suggests some future directions and challenges.