Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data. - Offers an innovative approach, focusing on how disease-associated pathways evolved - Explains how the fields of phylogeny and embryology have become closely tied to the fields of genetics and bioinformatics - Demonstrates how students and biomedical professionals can apply the knowledge obtained in this book to the theory and practice of precision medicine

This handbook reviews promising applications of psychedelics in treatment of such challenging psychiatric problems as posttraumatic stress disorder, major depression, substance use disorders, and end-of-life anxiety. Experts from multiple disciplines synthesize current knowledge on psilocybin, MDMA, ketamine, and other medical hallucinogens. The volume comprehensively examines these substances' neurobiological mechanisms, clinical effects, therapeutic potential, risks, and anthropological and historical contexts. Coverage ranges from basic science to practical clinical considerations, including patient screening and selection, dosages and routes of administration, how psychedelic-assisted sessions are structured and conducted, and management of adverse reactions.

Offers the very latest on the theory and practice of integrating mini-implant techniques into clinical practice This all-new second edition of The Orthodontic Mini-implant Clinical Handbook provides a thoroughly revised and expanded update to the theoretical and practical aspects of using mini-implants in orthodontic practice. Taking a practical step-by-step approach with hundreds of clinical images, it presents updated clinical techniques and new clinical cases, covering all topics of importance for utilising mini-implants. It also includes a new chapter on mini-implant anchored maxillary expansion appliances. It begins with a chapter that looks at mini-implant principles and potential complications, before moving onto clinical and design factors for maximising mini-implant success. Other chapters cover incisor retraction; molar distalisation and protraction; intrusion and anterior openbite treatments; bone anchored rapid maxillary expansion; orthognathic surgical uses; and ectopic teeth. Provides a comprehensive guide to both theoretical and practical advice for the use of mini-implants in orthodontic practice Covers updated clinical techniques and new clinical cases Presents a new chapter on mini-implant anchored maxillary expansion appliances Takes a highly illustrated step-by-step approach ideal for clinical practice The Orthodontic Mini-Implant Clinical Handbook is an essential resource to orthodontists, maxillofacial surgeons, practicing dentists, and anyone with an interest in mini-implant skeletal anchorage.

Taxonomic Guide to Infectious Diseases: Understanding the Biologic Classes of Pathogenic Organisms, Second Edition tackles the complexity of clinical microbiology by assigning every infectious organism to one of 40+ taxonomic classes and providing a description of the defining traits that apply to all the organisms within each class. This edition is an updated, revised and greatly expanded guide to the classes of organisms that infect humans. This book will provide students and clinicians alike with a simplified way to understand the complex fields of clinical microbiology and parasitology. - Focuses on human disease processes and includes numerous clinical tips for healthcare providers - Describes the principles of classification and explains why the science of taxonomy is vital to the fields of bioinformatics and modern disease research - Provides images of prototypical organisms for taxonomic classes - Includes a section that lists common taxonomic pitfalls and how they can be avoided

All too often, individuals engaged in the biomedical sciences assume that numeric data must be left to the proper authorities (e.g., statisticians and data analysts) who are trained to apply sophisticated mathematical algorithms to sets of data. This is a terrible mistake. Individuals with keen observational skills, regardless of their mathematical training, are in the best position to draw correct inferences from their own data and to guide the subsequent implementation of robust, mathematical analyses. Volume 2 of Logic and Critical Thinking in the Biomedical Sciences provides readers with a repertoire of deductive non-mathematical methods that will help them draw useful inferences from their own data.Volumes 1 and 2 of Logic and Critical Thinking in the Biomedical Sciences are written for biomedical scientists and college-level students engaged in any of the life sciences, including bioinformatics and related data sciences. - Demonstrates that a great deal can be deduced from quantitative data, without applying any statistical or mathematical analyses - Provides readers with simple techniques for quickly reviewing and finding important relationships hidden within large and complex sets of data - Using examples drawn from the biomedical literature, discusses common pitfalls in data interpretation and how they can be avoided

A collection of papers from the third Evolution of Psychotherapy Conference. The Evolution Conferences are organized by The Milton H. Erickson Foundation. The Erickson Foundation is a nonprofit educational organization. First published in 1997. Routledge is an imprint of Taylor & Francis, an informa company.

Increasingly, electroconvulsive therapy (ECT) is recognized as a proven, effective, and even life-saving intervention in certain mood and thought disorders when other treatments have had little or no effect. Despite the proven efficacy and safety of this standard treatment in psychiatry, its availability is variable. Part of this disparity in access is related to misunderstanding by laypersons regarding the treatment and its potential adverse effects. Adequate education and training of psychiatrists and their support staff are essential to ensuring patients' access to this vital treatment tool. The authors of Clinical Manual of Electroconvulsive Therapy offer this expansive yet reader-friendly volume to help psychiatrists successfully incorporate ECT into their clinical practices. It is also a valuable resource for medical students and psychiatric residents, as well as experienced clinicians and researchers. The book updates the 1985 original and 1998 second edition of Electroconvulsive Therapy: A Programmed Text, and provides readers with a scheduled approach to understanding the fundamental concepts of ECT while offering practical guidance for establishing and maintaining an ECT program. Topics include the history of ECT, indications for use, patient referral and evaluation, the basics of ECT, clinical applications, anesthetics and other medications, seizure monitoring and management, ictal motor and cardiovascular response, adverse effects, and maintenance ECT. Included are detailed descriptions of recent advances including ultra-brief pulse ECT, oxygenation, muscle relaxation, and other modifications that have made this very effective treatment much safer and more acceptable to patients. Currently, it is estimated that more than 100,000 people receive ECT treatments each year in the U.S. Indications for use of ECT are for mood disorders such as major depressive disorder and mania, and thought disorders including schizophrenia and schizoaffective disorder. Indications for use in other psychiatric disorders and general medical disorders such as Parkinson's disease, which appears to respond especially well to ECT, are reviewed as well. This highly-readable manual is a must-have for the library of any clinician interested in or currently practicing ECT: Provides background information on the origins of psychiatric treatments preceding ECT, including efforts using hydrotherapy and insulin comas Includes an algorithm for the management of ECT seizure adequacy Discusses contraindications as well as the potential adverse effects of ECT, including cognitive changes and cardiovascular complications Provides specific information about ECT device manufacturers, reprintable patient information sheets, and a written informed consent form This clinical manual comprehensively explores and explains the available knowledge regarding ECT -- based on extensive research over the past 70 years -- in order to help potential ECT clinicians make informed choices about the development and management of their ECT program.