Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.

Pesticides are now accepted as an integral part of modern agricultural production. This book provides analysis of the steps taken by national and international bodies working towards a cohesive global strategy for evaluating the safety of residues in food that result from approved pesticide uses. Also described is the role of the UN Food and Agriculture Organization (FAO), World Health Organization (WHO) and Codex Alimentarius in developing standards that protect the health of the consumers and ensure fair practices in the food trade. It goes on to look at the promotion of good agricultural practice in the use of pesticides and the need for control in their practical use. These include sampling, testing the compliance of marketed products against legal limits and verifying the effectiveness of the safety-based regulatory measures. This is a specialist book for those looking to go into the field of international food safety, for students and lecturers studying the topic, for policy makers working on public health and agricultural issues, and personnel responsible for taking samples and performing the analysis of pesticide formulations and residues.

The monographs in this volume summarize the safety data on 11 pesticides that could leave residues in food commodities. These pesticides are aminopyralid, atrazine, azinphos methyl, lamba-cyhalothrin, difenoconazole, dimethomorph, flusilazole, procymidone, profenofos, pyrimethanil and zoxamide. The data summarized in the toxicological monographs served as the basis for the acceptable daily intakes and acute reference doses that were established by the Meeting. This volume and previous volumes of JMPR toxicological evaluations, many of which were published in the FAO Plant Production and Protection Paperseries, contain information that is useful to companies that produce pesticides, government regulatory officers, industrial testing laboratories, toxicological laboratories and universities.

This book explores human exposure and consumer risk assessment in response to issues surrounding pesticide residues in food and drinking water. All the three main areas of consumer risk assessment including human toxicology, pesticide residue chemistry and dietary consumption are brought together and discussed. Includes the broader picture - the environmental fate of pesticides Takes an international approach with contributors from the European Union, USA and Australia Highlights the increasing concerns over food safety and the risks to humans

Concern about health effects from exposure to pesticides in foods is growing as scientists learn more about the toxic properties of pesticides. The Delaney Clause, a provision of the Food, Drug and Cosmetic Act, prohibits tolerances for any pesticide that causes cancer in test animals or in humans if the pesticide concentrates in processed food or feeds. This volume examines the impacts of the Delaney Clause on agricultural innovation and on the public's dietary exposure to potentially carcinogenic pesticide residues. Four regulatory scenarios are described to illustrate the effects of varying approaches to managing oncogenic pesticide residues in food.

The FAO/WHO Manual on development and use of FAO and WHO specifications for pesticides contains general principles and methodologies of the work undertaken by JMPS, is the continuous evaluation of new scientific developments and guidance documents. The Manual gives the historical background of the operation of the JMPS and describes the purpose of the work. The Manual is also used by countries as a guidance document in setting pesticide specifications. This 3rd revision of the Manual contains n ew methodologies/principles developed in recent 5 years and incorporates the current working principles applied by the JMPS.

This meeting, held in Berlin, Germany, on 18-27 September 2018, reviewed pesticide use patterns and good agricultural practices, data on the chemistry and composition of the pesticides, and methods of analysis for pesticide residues and recommended maximum residue levels. The report also contains information on acceptable daily intakes and acute reference doses of pesticides for humans, and general principles for the evaluation of pesticides. The recommendations of the joint FAO and WHO meeting, including further research and information, are proposed for use by Member governments of the respective agencies and other interested parties. The meeting was held in pursuance of recommendations, made by previous meetings and accepted by the governing bodies of FAO and WHO, that studies should be undertaken jointly by experts to evaluate possible hazards to humans arising from the occurrence of pesticide residues in foods.