Digital health and medical informatics have grown in importance in recent years, and have now become central to the provision of effective healthcare around the world. This book presents the proceedings of the 30th Medical Informatics Europe conference (MIE). This edition of the conference, hosted by the European Federation for Medical Informatics (EFMI) since the 1970s, was due to be held in Geneva, Switzerland in April 2020, but as a result of measures to prevent the spread of the Covid19 pandemic, the conference itself had to be cancelled. Nevertheless, because this collection of papers offers a wealth of knowledge and experience across the full spectrum of digital health and medicine, it was decided to publish the submissions accepted in the review process and confirmed by the Scientific Program Committee for publication, and these are published here as planned. The 232 papers are themed under 6 section headings: biomedical data, tools and methods; supporting care delivery; health and prevention; precision medicine and public health; human factors and citizen centered digital health; and ethics, legal and societal aspects. A 7th section deals with the Swiss personalized health network, and section 8 includes the 125 posters accepted for the conference. Offering an overview of current trends and developments in digital health and medical informatics, the book provides a valuable information resource for researchers and health practitioners alike.

In the bestselling The Physics of Star Trek, the renowned theoretical physicist Lawrence Krauss took readers on an entertaining and eye-opening tour of the Star Trek universe to see how it stacked up against the real universe. Now, responding to requests for more as well as to a number of recent exciting discoveries in physics and astronomy, Krauss takes a provocative look at how the laws of physics relate to notions from our popular culture -- not only Star Trek, but other films, shows, and popular lore -- from Independence Day to Star Wars to The X-Files. What's the difference between a flying saucer and a flying pretzel? Why didn't the aliens in Independence Day have to bother invading Earth to destroy it? What's new with warp drives? What's the most likely scenario for doomsday? Are ESP and telekinesis impossible? What do clairvoyance and time travel have in common? How might quantum mechanics ultimately affect the fate of life in the universe?

This thorough and detailed exposition is the result of an intensive month-long course on mirror symmetry sponsored by the Clay Mathematics Institute. It develops mirror symmetry from both mathematical and physical perspectives with the aim of furthering interaction between the two fields. The material will be particularly useful for mathematicians and physicists who wish to advance their understanding across both disciplines. Mirror symmetry is a phenomenon arising in string theory in which two very different manifolds give rise to equivalent physics. Such a correspondence has significant mathematical consequences, the most familiar of which involves the enumeration of holomorphic curves inside complex manifolds by solving differential equations obtained from a ``mirror'' geometry. The inclusion of D-brane states in the equivalence has led to further conjectures involving calibrated submanifolds of the mirror pairs and new (conjectural) invariants of complex manifolds: the Gopakumar-Vafa invariants. This book gives a single, cohesive treatment of mirror symmetry. Parts 1 and 2 develop the necessary mathematical and physical background from ``scratch''. The treatment is focused, developing only the material most necessary for the task. In Parts 3 and 4 the physical and mathematical proofs of mirror symmetry are given. From the physics side, this means demonstrating that two different physical theories give isomorphic physics. Each physical theory can be described geometrically, and thus mirror symmetry gives rise to a ``pairing'' of geometries. The proof involves applying $R\leftrightarrow 1/R$ circle duality to the phases of the fields in the gauged linear sigma model. The mathematics proof develops Gromov-Witten theory in the algebraic setting, beginning with the moduli spaces of curves and maps, and uses localization techniques to show that certain hypergeometric functions encode the Gromov-Witten invariants in genus zero, as is predicted by mirror symmetry. Part 5 is devoted to advanced topi This one-of-a-kind book is suitable for graduate students and research mathematicians interested in mathematics and mathematical and theoretical physics.

Understanding and modifying health behaviors plays an important part in healthcare. The need to change behaviors applies across a range of health contexts, from individual interventions to the clinically-delivered management of chronic diseases and rehabilitation. Telehealth or virtual care technology offers many possible advantages here, including cost-efficiency, scalability, personalization, and automated high volume data collection and analysis, but success will depend on the effectiveness of the design, implementation and deployment of IT-based methods. This book, which forms part of the Global Telehealth series, includes papers presented at Global Telehealth 2019 (GT2019), a National Symposium on the topic of IT-based Methods for Health Behaviours held in Adelaide, Australia on 5 July 2019. The 10 papers selected for inclusion here comprise only full-paper, blind peer-reviewed contributions received for the symposium and the subsequent call for further contributions. Topics range from the scientific theory of health behavior change, through technological approaches to active ageing and the implementation of the 10,000 steps project, to a discussion of digital infrastructure for the storing & sharing of internet of things, wearables and app-based research study data. The book will be of interest to all researchers, managers and healthcare practitioners working to bring about positive changes in health behavior.

This volume is based on lectures delivered at the 2020 AMS Short Course “Mean Field Games: Agent Based Models to Nash Equilibria,” held January 13–14, 2020, in Denver, Colorado. Mean field game theory offers a robust methodology for studying large systems of interacting rational agents. It has been extraordinarily successful and has continued to develop since its inception. The six chapters that make up this volume provide an overview of the subject, from the foundations of the theory to applications in economics and finance, including computational aspects. The reader will find a pedagogical introduction to the main ingredients, from the forward-backward mean field game system to the master equation. Also included are two detailed chapters on the connection between finite games and mean field games, with a pedestrian description of the different methods available to solve the convergence problem. The volume concludes with two contributions on applications of mean field games and on existing numerical methods, with an opening to machine learning techniques.

This book introduces a novel approach to discrete optimization, providing both theoretical insights and algorithmic developments that lead to improvements over state-of-the-art technology. The authors present chapters on the use of decision diagrams for combinatorial optimization and constraint programming, with attention to general-purpose solution methods as well as problem-specific techniques. The book will be useful for researchers and practitioners in discrete optimization and constraint programming. "Decision Diagrams for Optimization is one of the most exciting developments emerging from constraint programming in recent years. This book is a compelling summary of existing results in this space and a must-read for optimizers around the world." [Pascal Van Hentenryck]

This clear and compelling textbook provides a complete survey of the field of child abuse and neglect from the perspective of modern developmental attachment theory. It starts by describing the ways in which attachment difficulties manifest themselves in children's behaviour, and goes on looking at abuse, neglect, and compound cases of abuse and neglect, backing it all up with empirical research evidence and vivid case material. In its final section, it provides a comprehensive review of attachment-based interventions. Written by an extremely respected and successful author, this book, anchored in research evidence, places its emphasis on practice implementation and aims at answering all the kinds of questions practitioners and student practitioners specialising in child welfare are most likely to ask.