The alarm calls of birds make them difficult for predators to locate, while the howl of wolves and the croak of bullfrogs are designed to carry across long distances. From an engineer's perspective, how do such specialized adaptations among living things really work? And how does physics constrain evolution, channeling it in particular directions? Writing with wit and a richly informed sense of wonder, Denny and McFadzean offer an expert look at animals as works of engineering, each exquisitely adapted to a specific manner of survival, whether that means spinning webs or flying across continents or hunting in the dark-or writing books. This particular book, containing more than a hundred illustrations, conveys clearly, for engineers and nonengineers alike, the physical principles underlying animal structure and behavior. Pigeons, for instance-when understood as marvels of engineering-are flying remote sensors: they have wideband acoustical receivers, hi-res optics, magnetic sensing, and celestial navigation. Albatrosses expend little energy while traveling across vast southern oceans, by exploiting a technique known to glider pilots as dynamic soaring. Among insects, one species of fly can locate the source of a sound precisely, even though the fly itself is much smaller than the wavelength of the sound it hears. And that big-brained, upright Great Ape? Evolution has equipped us to figure out an important fact about the natural world: that there is more to life than engineering, but no life at all without it.

Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.

From an engineer’s perspective, how do specialized adaptations among living things really work? Writing with wit and a richly informed sense of wonder, Denny and Alan offer an expert look at animals—including humans—as works of evolutionary engineering, each exquisitely adapted to a specific manner of survival.

Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.

Arranging the transportation of animals at research facilities is often an ordeal. There is a confusing patchwork of local, national, and international regulations; a perceived lack of high-quality shipping services; a dearth of science-based good practices; and a lack of biosafety standards. It's a challenge â€"and an impediment to biomedical research. Guidelines for the Humane Transportation of Research Animals identifies the current problems encountered in the transportation of research animals and offers recommendations aimed at local and federal officials to rectify these problems. This book also includes a set of good practices based on the extensive body of literature on transportation of agricultural animals, universal concepts of physiology, and a scientific understanding of species-specific needs and differences. Good practices were developed by the committee to address thermal environment, space requirements, food and water requirements, social interaction, monitoring of transportation, emergency procedures, personnel training, and biosecurity. Guidelines for the Humane Transportation of Research Animals is an essential guide for all researchers, animal care technicians, facilities managers, administrators, and animal care and use committees at research institutions.

This book is unlike others on the emotionally charged subject of the moral and social issues raised by genetically engineering animals. Nontechnical and anecdotal, it attempts to inform, not inflame, the reader about the problems society must address.

A comprehensive and accessible survey of the best current accomplishments of GMO research in all their complexity and ramifications. The authors introduce the fundamentals of biotechnology as a scientific discipline, show how GMO research is conducted today, discuss the problems that have arisen from genetic technology and the tools needed to resolve them, and describes how GMO-derived technology may impact our lives in the future. On the technical side, the authors examine a wide range of current technologies employed for constructing GMOs, and describe approaches to novel research, appropriate protocols, and the process of constructing and screening a GMO. The discussion of plant and animal cells covers new strategies employed and the large-scale expression and purification of recombinant products in cultured cells. Social political, and legal issues are also discussed.