A review of research on the ecology of Lyme disease in North America describes how humans get sick, why some years and places are so risky and others not, and offers a new understanding that embraces the complexity of species and their interactions.

Lyme disease--virtually unknown in the United States only a decade ago--has now been reported from almost every state; in the Northeast, it has become a major public health crisis. Under the name of borreliosis, the disease is also common in Europe. As Americans have become aware of the hazard they face from Lyme disease, they have become anxious to know how to avoid or control the disease. But the complex ecological interactions of Lyme disease make that extremely difficult. The disease is caused by a microorganism, a spirochete, which is carried by tiny ticks. The ticks, in turn, are transported from place to place by their hosts: humans, deer, white-tailed mice, dogs, lizards, and many other animals and birds. Both ticks and their hosts serve as a reservoir for the disease. As with any tick-borne disease, the best hope of prevention lies in understanding and interrupting the lifecycle of the microorganism, its vectors, and their hosts. This book is the first attempt to survey the natural history, ecology, population dynamics, geography, and environmental management of Lyme disease. Eighteen leading American researchers on Lyme disease explain the current state of knowledge and comment candidly on the theoretical and practical advantages and difficulties with each technique of surveillance, self-protection, and tick control. The book includes suggestions for personal protection against the disease, This is an essential resource for naturalists, ecologists, physicians, nurses, epidemiologists, public health officials, entomologists, veterinarians, pest control operators, wildlife managers, town planners, and anyone concerned with Lyme disease.

Twenty-first century progress against infectious diseases is threatened by urbanization, population growth, war refugees, changing sexual standards, and a host of other factors that open doors to the transmission of deadly pathogens. Infectious Diseases in an Age of Change reports on major infectious diseases that are on the rise today because of changing conditions and identifies urgently needed public health measures. This volume looks at the range of factors that shape the epidemiology of infectious diseasesâ€"from government policies to economic trends to family practices. Describing clinical characteristics, transmission, and other aspects, the book addresses major infectious threatsâ€"sexually transmitted diseases, Lyme disease, human cytomegalovirus, diarrheal diseases, dengue fever, hepatitis viruses, HIV, and malaria. The authors also look at the rising threat of drug-resistant strains of tuberculosis, rapid exhaustion of the weapons to fight bacterial infections, and prospects for vaccinations and eradication of pathogens. Infectious Diseases in an Age of Change will be important to public health policymakers, administrators, and providers as well as epidemiologists and researchers.

This book brings together expert opinions from scientists to consider the evidence for climate change and its impacts on ticks and tick-borne infections. It considers what is meant by 'climate change', how effective climate models are in relation to ecosystems, and provides predictions for changes in climate at global, regional and local scales relevant for ticks and tick-borne infections. It examines changes to tick distribution and the evidence that climate change is responsible. The effect of climate on the physiology and behaviour of ticks is stressed, including potentially critical impacts on the tick microbiome. Given that the notoriety of ticks derives from pathogens they transmit, the book considers whether changes in climate affect vector capacity. Ticks transmit a remarkable range of micro- and macro-parasites many of which are pathogens of humans and domesticated animals. The intimacy between a tick-borne agent and a tick vector means that any impacts of climate on a tick vector will impact tick-borne pathogens. Most obviously, such impacts will be apparent as changes in disease incidence and prevalence. The evidence that climate change is affecting diseases caused by tick-borne pathogens is considered, along with the potential to make robust predictions of future events.