The brachytherapy process requires consistent reference dosimetry that is traceable to metrological primary standards and common procedures to be followed for reference dosimetry globally. The Code of Practice is addressed to both Secondary Standards Dosimetry Laboratories and hospitals. It fulfills the need for a systematic and internationally unified approach to the calibration and use of vented well-type re-entrant ionisation chambers in determining the strength of brachytherapy sources with intensities measurable by such detectors. The dosimetry formalism as well as common procedures for calibration, reference dosimetry, reference-class instrument assessment and commissioning of the well-type ionisation chamber system are provided.

The brachytherapy process requires consistent reference dosimetry that is traceable to metrological primary standards and common procedures to be followed for reference dosimetry globally. The Code of Practice is addressed to both Secondary Standards Dosimetry Laboratories and hospitals. It fulfils the need for a systematic and internationally unified approach to the calibration and use of vented well-type re-entrant ionisation chambers in determining the strength of brachytherapy sources with intensities measurable by such detectors. The dosimetry formalism as well as common procedures for calibration, reference dosimetry, reference-class instrument assessment and commissioning of the well-type ionisation chamber system are provided.

Brachytherapy is an essential component of the curative treatment of cervical cancer, a disease with high incidence in many developing countries The IAEA supports the use of high dose rate brachytherapy for centres with a large number of patients with this disease. HDR brachytherapy is also used in other common cancers such as breast cancer, lung, esophagus and prostate. This publication provides guidance to radiation oncologists, medical physicists and planners on establishing and operating a high dose rate brachytherapy unit with modern standards and presents the main issues to be addressed for its effective and safe operation.

On request, the IAEA performs comprehensive audits of radiotherapy programmes to assess the whole process, including aspects such as organization, infrastructure and clinical and medical physics components. The objective of a comprehensive clinical audit is to review and evaluate the quality of all components of the practice of radiotherapy at the institution, including its professional competence, with a view to quality improvement. A multidisciplinary team, known as Quality Assurance Team in Radiation Oncology (QUATRO), comprising a radiation oncologist. a medical physicist and a radiation therapist, are required to carry out the audit. The present publication provides revisions of the QUATRO guidelines published in 2007, by incorporating new procedures relevant to newer technologies and modalities that have become routinely used in radiotherapy centres in the interim period.

Modern brachytherapy is one of the most important oncological treatment modalities requiring an integrated approach that utilizes new technologies, advanced clinical imaging facilities, and a thorough understanding of the radiobiological effects on different tissues, the principles of physics, dosimetry techniques and protocols, and clinical expertise. A complete overview of the field, Comprehensive Brachytherapy: Physical and Clinical Aspects is a landmark publication, presenting a detailed account of the underlying physics, design, and implementation of the techniques, along with practical guidance for practitioners. Bridging the gap between research and application, this single source brings together the technological basis, radiation dosimetry, quality assurance, and fundamentals of brachytherapy. In addition, it presents discussion of the most recent clinical practice in brachytherapy including prostate, gynecology, breast, and other clinical treatment sites. Along with exploring new clinical protocols, it discusses major advances in imaging, robotics, dosimetry, Monte Carlo-based dose calculation, and optimization.

This book reports the majority of lectures given during the NATO Advanced Study Institute ASI-982996, which was held at the European Scientific Institute of Archamps (ESI, Archamps – France) from November 15 to November 27, 2007. The ASI course was structured in two parts: the first was dedicated to what is often called “teletherapy”, i. e. radiotherapy with external beams, while the second focused on internal radiotherapy, also called “brachytherapy” or “curietherapy” in honour of Madame Curie who initiated the technique about a century ago. This ASI took place after the European School of Medical Physics, which devoted a 3 week period to medical imaging, a subject complementary to the topics of this book. Courses devoted to nuclear medicine and digital imaging techniques are collected in two volumes of the NATO Science Series entitled “Physics for Medical Imaging Applications” (ISBN 978-1-4020-5650-5) and “Molecular imaging: computer reconstruction and practice” (ISBN 978-1-4020- 8751-6). Every year in autumn ESI organises the European School of Medical Physics, which covers a large spectrum of topics ranging from Medical Imaging to Radiotherapy, over a period of 5 weeks. Thanks to the Cooperative Science and Technology sub-programme of the NATO Science Division, weeks four and five were replaced this year by the ASI course dedicated to “Physics of Modern Radiotherapy & Brachytherapy”. This allowed the participation of experts and students from 20 different countries, with diverse cultural background and p- fessional experience.

Co-published by the European Medical Imaging Technology e-Encyclopaedia for Lifelong Learning (EMITEL) consortium and supported by the International Organization for Medical Physics (IOMP), Encyclopaedia of Medical Physics contains nearly 2,800 cross-referenced entries relating to medical physics and associated technologies. Split into two convenie