Introduces thermodynamics, presents a history of the field, and discusses the advances in thermometry.

This is a sequel to the author's book entitled “Entropy Demystified” (Published by World Scientific, 2007). The aim is essentially the same as that of the previous book by the author: to present Entropy and the Second Law as simple, meaningful and comprehensible concepts. In addition, this book presents a series of “experiments” which are designed to help the reader discover entropy and the Second Law. While doing the experiments, the reader will encounter three most fundamental probability distributions featuring in Physics: the Uniform, the Boltzmann and the Maxwell-Boltzmann distributions. In addition, the concepts of entropy and the Second Law will emerge naturally from these experiments without a tinge of mystery. These concepts are explained with the help of a few familiar ideas of probability and information theory.The main “value” of the book is to introduce entropy and the Second Law in simple language which renders it accessible to any reader who can read and is curious about the basic laws of nature. The book is addressed to anyone interested in science and in understanding natural phenomenon. It will afford the reader the opportunity to discover one of the most fundamental laws of physics — a law that has resisted complete understanding for over a century. The book is also designed to be enjoyable.There is no other book of its kind (except “Entropy Demystified” by the same author) that offers the reader a unique opportunity to discover one of the most profound laws — sometimes viewed as a mysterious — while comfortably playing with familiar games. There are no pre-requisites expected from the readers; all that the reader is expected to do is to follow the experiments or imagine doing the experiments and reach the inevitable conclusions.

This is a sequel to the author’s book entitled “Entropy Demystified.” The aim is essentially the same as that of the previous book by the author: to present Entropy and the Second Law as simple, meaningful and comprehensible concepts. In addition, this book presents a series of “experiments” which are designed to help the reader discover entropy and the Second Law. While doing the experiments, the reader will encounter no unexpected results, and concepts of entropy and the Second Law will emerge naturally from these experiments without a tinge of mystery. These concepts are explained with the help of a few familiar ideas of probability and a 20-question game. The main “value” of the book is to introduce entropy and the Second Law in simple language which renders it accessible to any reader who can read and is curious about the basic laws of nature. The book is addressed to anyone interested in science and in understanding natural phenomenon. It will give the reader the opportunity to discover one of the most fundamental laws of physics — a law that has resisted complete understanding for over a century. The book is also designed to be enjoyable. There is no other book of its kind (except “Entropy Demystified” by the same author) that offers the reader a unique opportunity to discover one of the most profound laws — sometimes viewed as a mysterious law — without the tinge mystery. There are no pre-requisites expected of the readers; all that the reader is expected to do is to follow the experiments or imagine doing the experiments and reach the inevitable conclusions.

This book offers an easy to read, all-embracing history of thermodynamics. It describes the long development of thermodynamics, from the misunderstood and misinterpreted to the conceptually simple and extremely useful theory that we know today. Coverage identifies not only the famous physicists who developed the field, but also engineers and scientists from other disciplines who helped in the development and spread of thermodynamics as well.

Applied Biophysics for Drug Discovery is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns. This text emphasizes practical considerations for selecting and deploying core biophysical method, including but not limited to ITC, SPR, and both ligand-detected and protein-detected NMR. Topics covered include: • Design considerations in biophysical-based lead screening • Thermodynamic characterization of protein-compound interactions • Characterizing targets and screening reagents with HDX-MS • Microscale thermophoresis methods (MST) • Screening with Weak Affinity Chromatography • Methods to assess compound residence time • 1D-NMR methods for hit identification • Protein-based NMR methods for SAR development • Industry case studies integrating multiple biophysical methods This text is ideal for academic investigators and industry scientists planning hit characterization campaigns or designing and optimizing screening strategies.

Take some heat off the complexity of thermodynamics Does the mere thought of thermodynamics make you sweat? It doesn't have to! This hands-on guide helps you score your highest in a thermodynamics course by offering easily understood, plain-English explanations of how energy is used in things like automobiles, airplanes, air conditioners, and electric power plants. Thermodynamics 101 — take a look at some examples of both natural and man-made thermodynamic systems and get a handle on how energy can be used to perform work Turn up the heat — discover how to use the first and second laws of thermodynamics to determine (and improve upon) the efficiency of machines Oh, behave — get the 411 on how gases behave and relate to one another in different situations, from ideal-gas laws to real gases Burn with desire — find out everything you need to know about conserving mass and energy in combustion processes Open the book and find: The laws of thermodynamics Important properties and their relationships The lowdown on solids, liquids, and gases How work and heat go handin hand The cycles that power thermodynamic processes Chemical mixtures and reactions Ten pioneers in thermodynamics Real-world applications of thermodynamic laws and concepts Learn to: Master the concepts and principles of thermodynamics Develop the problem-solving skills used by professional engineers Ace your thermodynamics course