The main subject division of this book include the theory of Diffuse reflectance spectroscopy; measurement and standardization of diffuse reflectance; instrumentation; application to color measurement and physical, inorganic, and organic chemistry; and applications in chromatographic analysis.While the use of reflectance spectroscopy dates from the 1920s, it has only been in the last decade that its analytical potential has been developed. Interestingly, much of the early research involved industrial uses where measurement of color was required. The development and acceptance of thin-layer chromatography has opened up new areas of analysis for the application of this technique.It is not the purpose of this book to delve deeply into the theoretical aspects of reflectance spectroscopy, as this book has already been done in several previous books. Insofar as it is possible, this book is an up-to-date guide to instruments and techniques intended primarily for the chemical analyst, though it is hoped that it may contain information of interest to other scientists. The potential for the application of this technique is great and the authors feel confident that the coming decade will see many interesting developments in this type of spectroscopy study, particularly in the field of analysis.

The main subject division of this book include the theory of Diffuse reflectance spectroscopy; measurement and standardization of diffuse reflectance; instrumentation; application to color measurement and physical, inorganic, and organic chemistry; and applications in chromatographic analysis.While the use of reflectance spectroscopy dates from the 1920s, it has only been in the last decade that its analytical potential has been developed. Interestingly, much of the early research involved industrial uses where measurement of color was required. The development and acceptance of thin-layer chromatography has opened up new areas of analysis for the application of this technique.It is not the purpose of this book to delve deeply into the theoretical aspects of reflectance spectroscopy, as this book has already been done in several previous books. Insofar as it is possible, this book is an up-to-date guide to instruments and techniques intended primarily for the chemical analyst, though it is hoped that it may contain information of interest to other scientists. The potential for the application of this technique is great and the authors feel confident that the coming decade will see many interesting developments in this type of spectroscopy study, particularly in the field of analysis.

Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. - Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it - Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations - Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS