This book is about model-based diagnosis of a class of discrete-event systems called active systems. Roughly, model-based diagnosis is the task of finding out the faulty components of a physical system based on the observed behavior and the system model. An active system is the abstraction of a physical artefact that is modeled as a network of com municating automata. For example, the protection apparatus of a power transmission network can be conveniently modeled as an active system, where breakers, protection devices, and lines are naturally described by finite state machines. The asynchronous occurrence of a short circuit on a line or a bus-bar causes the reaction of the protection devices, which aims to isolate the shorted line. This reaction can be faulty and several lines might be eventually isolated, rather than the shorted line only. The diagnostic problem to be solved is uncovering the faulty devices based the visible part of the reaction. Once the diagnosis task has been on accomplished, the produced results are exploited to fix the apparatus (and also to localize the short circuit, in this sample case). Interestingly, the research presented in this book was triggered a decade ago by a project 011 short circuit localization, conducted by ENEL, the Italian electricity board, along with other industrial and academic European partners.

This book is an up-to-date self-contained compendium of the research carried out by the authors on model-based diagnosis of a class of discrete-event systems called active systems. After defining the diagnosis problem, the book copes with a variety of reasoning mechanisms that generate the diagnosis, possibly within a monitoring setting. The book is structured into twelve chapters, each of which has its own introduction and concludes with bibliographic notes and itemized summaries. Concepts and techniques are presented with the help of numerous examples, figures, and tables, and when appropriate these concepts are formalized into propositions and theorems, while detailed algorithms are expressed in pseudocode. This work is primarily intended for researchers, professionals, and graduate students in the fields of artificial intelligence and control theory.

Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.

Expert guidance on theory and practice in condition-based intelligent machine fault diagnosis and failure prognosis Intelligent Fault Diagnosis and Prognosis for Engineering Systems gives a complete presentation of basic essentials of fault diagnosis and failure prognosis, and takes a look at the cutting-edge discipline of intelligent fault diagnosis and failure prognosis technologies for condition-based maintenance. It thoroughly details the interdisciplinary methods required to understand the physics of failure mechanisms in materials, structures, and rotating equipment, and also presents strategies to detect faults or incipient failures and predict the remaining useful life of failing components. Case studies are used throughout the book to illustrate enabling technologies. Intelligent Fault Diagnosis and Prognosis for Engineering Systems offers material in a holistic and integrated approach that addresses the various interdisciplinary components of the field--from electrical, mechanical, industrial, and computer engineering to business management. This invaluably helpful book: * Includes state-of-the-art algorithms, methodologies, and contributions from leading experts, including cost-benefit analysis tools and performance assessment techniques * Covers theory and practice in a way that is rooted in industry research and experience * Presents the only systematic, holistic approach to a strongly interdisciplinary topic

This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

There have been calls to revisit the experiences of TB screening campaigns that were widely applied in Europe and North America in the mid-20th century, as well as more recent experiences with TB screening in countries with a high burden of the disease, and to assess their possible relevance for TB care and prevention in the 21st century. In response, WHO has developed guidelines on screening for active TB. An extensive review of the evidence has been undertaken. The review suggests that screening, if done in the right way and targeting the right people, may reduce suffering and death, but the review also highlights several reasons to be cautious. As discussed in detail in this book, there is a need to balance potential benefits against the risks and costs of screening; this conclusion is mirrored by the history of TB screening. This publication presents the first comprehensive assessment by WHO of the appropriateness of screening for active TB since the recommendations made in 1974 by the Expert Committee. However, the relative effectiveness and cost effectiveness of screening remain uncertain, a point that is underscored by the systematic reviews presented in this guideline. Evidence suggests that some risk groups should always be screened, whereas the prioritization of other risk groups as well as the choice of screening approach depend on the epidemiology, the health-system context, and the resources available. This book sets out basic principles for prioritizing risk groups and choosing a screening approach; it also emphasizes the importance of assessing the epidemiological situation, adapting approaches to local situations, integrating TB screening into other health-promotion activities, minimizing the risk of harm to individuals, and engaging in continual monitoring and evaluation. It calls for more and better research to assess the impact of screening and to develop and evaluate new screening tests and approaches.