Keratoplasty is the transplantation of all or part of the cornea to repair scarred or damaged tissue. A femtosecond laser is a laser which emits ultrashort pulses, used for minimally invasive corneal surgery. This book is a concise guide to the technique of femtosecond laser-assisted keratoplasty. Beginning with an introduction to the technology, the following chapters discuss its use for different disorders. This practical text is based on the surgical experience of its internationally recognised authors from Spain, Germany, France and the USA. It includes more than 230 full colour clinical photographs and illustrations to enhance learning. Key points Concise guide to the corneal transplantation procedure of femtosecond laser-assisted keratoplasty Covers key technologies and uses for different disorders Internationally recognised author and editor team Includes more than 230 clinical photographs and illustrations

In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites usually have an anaerobic metabolism, while blood parasites have an aerobic metabolism, intracellular parasites escape the immune system, while extracellular parasites evade the immune system, usually by antigenic variation. Comprehensive genome data now being available allow us to address profound scientific questions, such as which traits enable the parasite to survive in the human host, which to cause disease and which can be used as drug targets. This book intends to give an overview of the state of knowledge on “the molecules” of protozoan parasites – on their genomes, proteomes, glycomes and lipidomes.

This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.

Based on the 1981 International Conference on Reproductive Immunology, this is a comprehensive survey of the rapidly-expanding field. The work of many distinguished contributors is presented in three parts: I. The Embryo as Antigen, II. The Placenta as Immunological Barrier, and III. Regulation of the Maternal Immune Response.

Filarial nematodes constitute and important group of human pathogens in tropical regions of the world. Diseases associated with these worms are generally separated into two categories: filariasis, caused by infections of lymphatic dwelling parasites and onchocerciasis, or river blindness, caused by infections of Onchocerca volvulus. Other filariae specifically infect humans and it is likely that zoonotic filarial infections may alter the outcome of infections with human parasites. The chapters in this book will cover concepts that, in most instances, overlap all of these parasites as well as focus on new and emerging ideas. The Filaria, volume five of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.