Polychlorinated Biphenyls (PCBs) are synthetic chlorinated hydrocarbon compounds, produced commercially since 1929 for use in a variety of products including plastics and adhesives, surface coatings, inks, flame retardants, pesticides and paints. PCBs are environmentally persistent, and accumulate in the food chain. They are designated by the Stockholm Convention on Persistent Organic Pollutants as persistent pollutants, and many countries have severely restricted or banned the production of PCBs. This report evaluates the effects of PCBs on human health, caused due to exposure by inhaling contaminated air or ingesting contaminated food and water.