Brain imaging has been successfully used to generate image-based biomarkers for various neurological and psychiatric disorders, such as Alzheimer’s and related dementias, Parkinson’s disease, stroke, traumatic brain injury, brain tumors, depression, schizophrenia, etc. However, accurate brain image-based diagnosis at the individual level remains elusive, and this applies to the diagnosis of neuropathological diseases as well as clinical syndromes. In recent years, deep learning techniques, due to their ability to learn complex patterns from large amounts of data, have had remarkable success in various fields, such as computer vision and natural language processing. Applying deep learning methods to brain imaging-assisted diagnosis, while promising, is facing challenges such as insufficiently labeled data, difficulty in interpreting diagnosis results, variations in data acquisition in multi-site projects, integration of multimodal data, clinical heterogeneity, etc. The goal of this research topic is to gather cutting-edge research that showcases the application of deep learning methods in brain imaging for the diagnosis of neurological and psychiatric disorders. We encourage submissions that demonstrate novel approaches to overcome various abovementioned difficulties and achieve more accurate, reliable, generalizable, and interpretable diagnosis of neurological and psychiatric disorders in this field.

Machine Learning is an area of artificial intelligence involving the development of algorithms to discover trends and patterns in existing data; this information can then be used to make predictions on new data. A growing number of researchers and clinicians are using machine learning methods to develop and validate tools for assisting the diagnosis and treatment of patients with brain disorders. Machine Learning: Methods and Applications to Brain Disorders provides an up-to-date overview of how these methods can be applied to brain disorders, including both psychiatric and neurological disease. This book is written for a non-technical audience, such as neuroscientists, psychologists, psychiatrists, neurologists and health care practitioners. - Provides a non-technical introduction to machine learning and applications to brain disorders - Includes a detailed description of the most commonly used machine learning algorithms as well as some novel and promising approaches - Covers the main methodological challenges in the application of machine learning to brain disorders - Provides a step-by-step tutorial for implementing a machine learning pipeline to neuroimaging data in Python

Notable experts in the field of neuroimaging provide comprehensive overviews of advances in functional and structural aspects of both common and uncommon brain disorders. Functional imaging is evolving quickly but researchers and clinicians do not always have a strong understanding of the fundamental basis of the imaging techniques that they use. By focusing on both structure and function this book will provide a strong foundation for emerging developments in the field.