Published in 2004: This new edition of Comprehensive Geriatric Oncology still offers an exhaustive review of the biology of cancer and aging, of the epidemiologic trends in the country and in the world, and of the clinical trials that concern cancer prevention and cancer treatment in the elderly.

Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.

Half the population of dogs and cats aged 10 and over will die of neoplasia. The bonds that clients have developed with their older pets are especially strong and drive the increasing demand for more proficient and highly compassionate medical treatment of companion animals diagnosed with cancer. This book offers more than just a competent clinical approach to the most common tumors in dogs and cats. This book also offers a focus on the special needs of geriatric pets and their owners. Amply illustrated with dozens of case studies representative of those regularly encountered in practice, Canine and Feline Geriatric Oncology will provide readers with the tools needed to diagnose and treat aging pets with cancer, and to help clients make the best decisions for themselves and for the animals with whom they share their lives. Canine and Feline Geriatric Oncology is a unique resource. It is a useful oncology reference for specialists, veterinarians in general practice, veterinary technicians, and clinic staff. The many "what ifs" that the practitioner inevitably faces in interactions with clients and their aging pets with cancer are presented and discussed. Special Features: * Focuses on the special needs of geriatric pets and their caregivers; * Offers direction in the diagnosis and treatment of aging pets with cancer; * Addresses many of the "what ifs" that arise in interactions with clients and aging pets with cancer; * Amply illustrated with full color throughout; * A valuable reference for practicing veterinarians, technicians, hospital staff, and professionals involved in supportive counseling for pet caregivers.

This book is intended as a comprehensive resource for clinicians and researchers seeking in-depth information on geriatric oncology. The coverage encompasses epidemiology, the biology and (patho)physiology of aging and cancer, geriatric assessment and management, hematologic malignancies, solid tumors, issues in patient care, and research methods. Since cancer is a disease of aging and people are living longer, most cancer patients are now aged 70 and older. Yet the more we age, the more diverse we become in terms of our health, biologic fitness, and cancer behavior. Typically, however, general oncology clinical trials address only a selected healthier and younger population of patients. Geriatric oncology is the area of oncology that addresses these issues but while a wealth of knowledge has been accumulated, information is often difficult to retrieve or insufficiently detailed. The SpringerReference program, in which this book is published, offers an ideal format for overcoming these limitations since it combines thorough coverage with access to living editions constantly updated chapter by chapter via a dynamic peer-review process, ensuring that information remains current and pertinent.

This book offers an up-to-date review on the principles and practice of multidimensional assessment and management of the older individual, which represents the cornerstone of modern clinical practice in the elderly. The early chapters cover the main elements and scope of the comprehensive geriatric approach and explain the pathways of care from screening and case finding through to in-depth assessment and treatment planning. Subsequent chapters review the evidence of how best to apply the multidimensional assessment and management approach in defined healthcare settings and within specific clinical areas, such as cancer and surgery. Finally, the education and training challenges are reviewed and the prospects for future clinical service and research in this important field are examined. The book is very timely given the recent advances in application of this approach, which reflect the growing international realization that older people are “core business” in many clinical areas where the role of specialist geriatric medicine has hitherto been limited. Accordingly, the book will be relevant to a wide range of clinicians. The authorship comprises many of the best known and widely published experts in their respective fields.

Because cancer in the older adult may be present in combination with other chronic conditions, including dementia and frailty, multidisciplinary care is especially important. This book provides nurses with essential information on the care and treatment of the older adult with cancer, including: An overview of cancer in the older adult, and barriers to treatment Prevention and screening of cancer in the older adult How to perform a comprehensive geriatric assessment, as a method for planning multidisciplinary care Practical applications of qualiy of life assessment and decision analysis Special considerations in radiation therapy and chemotherapy with the older adult Social and caregiver issues This book reflects lessons learned from a nurse-physician team who planned and implemented the Senior Adult Oncology Program at the.Moffit Cancer Center and Research Institute in Florida.

The risk of cancer increases with age, and the number of older adults seeking treatment is increasing dramatically in line with the aging population. The care of older patients differs from that of younger adults because of differences in the biology of the tumor, age-related differences in host physiology, comorbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy. Practical Geriatric Oncology is a comprehensive, evidence-based text that synthesizes the growing literature in this field and provides practical guidelines to the care of older adults with cancer. Coverage includes patient assessment, management of solid tumors and hematologic malignancies, the impact of age on the pharmacology of cancer therapy, surgical oncology and radiation oncology in the older adult, symptom management and supportive care. In addition to serving as core reading for oncologists and hematologists, the book will also be a useful work for other healthcare professionals who provide oncology care, including surgeons, radiation oncologists, palliative care doctors, primary care providers, geriatricians and nurses.