Quantitative Trait Loci

Quantitative Trait Loci
Title Quantitative Trait Loci PDF eBook
Author Nicola J. Camp
Publisher Springer Science & Business Media
Pages 362
Release 2008-02-03
Genre Medical
ISBN 1592591760

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In Quantitative Trait Loci: Methods and Protocols, a panel of highly experienced statistical geneticists demonstrate in a step-by-step fashion how to successfully analyze quantitative trait data using a variety of methods and software for the detection and fine mapping of quantitative trait loci (QTL). Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and variations in method ease the way to understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov Chain Monte Carlo method for joint linkage and segregation analysis.

Genetic Dissection of Complex Traits

Genetic Dissection of Complex Traits
Title Genetic Dissection of Complex Traits PDF eBook
Author D.C. Rao
Publisher Academic Press
Pages 788
Release 2008-04-23
Genre Medical
ISBN 0080569110

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The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Five sections on the latest advances in complex traits Methods for testing with ethical, legal, and social implications Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more

Genetics and Analysis of Quantitative Traits

Genetics and Analysis of Quantitative Traits
Title Genetics and Analysis of Quantitative Traits PDF eBook
Author Michael Lynch
Publisher Sinauer Associates Incorporated
Pages 980
Release 1998-01
Genre Science
ISBN 9780878934812

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Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.

Quantitative Trait Loci Analysis in Animals

Quantitative Trait Loci Analysis in Animals
Title Quantitative Trait Loci Analysis in Animals PDF eBook
Author Joel Ira Weller
Publisher CABI
Pages 288
Release 2009
Genre Technology & Engineering
ISBN 1845937341

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Quantitative Trait Loci (QTL) is a topic of major agricultural significance for efficient livestock production. This book covers various statistical methods that have been used or proposed for detection and analysis of QTL and marker-and gene-assisted selection in animal genetics and breeding.

Marker-assisted Selection

Marker-assisted Selection
Title Marker-assisted Selection PDF eBook
Author Food and Agriculture Organization of the United Nations
Publisher Food & Agriculture Org.
Pages 498
Release 2007
Genre Business & Economics
ISBN 9789251057179

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A comprehensive description and assessment of the use of marker-assisted selection for increasing the rate of genetic gain in crops, livestock, forestry and fish, including the related policy, FAO's tradition of dealing with issues of importance to agricultural and economic development in a multidisciplinary and cross-sectoral manner.

Molecular Dissection of Complex Traits

Molecular Dissection of Complex Traits
Title Molecular Dissection of Complex Traits PDF eBook
Author Andrew H. Paterson
Publisher CRC Press
Pages 328
Release 2019-09-17
Genre Science
ISBN 9781420049381

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In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail. Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing new developments in thi

Genome-Wide Association Studies and Genomic Prediction

Genome-Wide Association Studies and Genomic Prediction
Title Genome-Wide Association Studies and Genomic Prediction PDF eBook
Author Cedric Gondro
Publisher Humana Press
Pages 0
Release 2013-06-12
Genre Science
ISBN 9781627034463

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With the detailed genomic information that is now becoming available, we have a plethora of data that allows researchers to address questions in a variety of areas. Genome-wide association studies (GWAS) have become a vital approach to identify candidate regions associated with complex diseases in human medicine, production traits in agriculture, and variation in wild populations. Genomic prediction goes a step further, attempting to predict phenotypic variation in these traits from genomic information. Genome-Wide Association Studies and Genomic Prediction pulls together expert contributions to address this important area of study. The volume begins with a section covering the phenotypes of interest as well as design issues for GWAS, then moves on to discuss efficient computational methods to store and handle large datasets, quality control measures, phasing, haplotype inference, and imputation. Later chapters deal with statistical approaches to data analysis where the experimental objective is either to confirm the biology by identifying genomic regions associated to a trait or to use the data to make genomic predictions about a future phenotypic outcome (e.g. predict onset of disease). As part of the Methods in Molecular Biology series, chapters provide helpful, real-world implementation advice.