Lipid Nanocarriers for Drug Targeting presents recent advances in the area of lipid nanocarriers. The book focuses on cationic lipid nanocarriers, solid lipid nanocarriers, liposomes, thermosensitive vesicles, and cubosomes, with applications in phototherapy, cosmetic and others. As the first book related to lipid nanocarriers and their direct implication in pharmaceutical nanotechnology, this important reference resource is ideal for biomaterials scientists and those working in the medical and pharmaceutical industries that want to learn more on how lipids can be used to create more effective drug delivery systems. - Highlights the most commonly used types of lipid nanocarriers and explains how they are applied in pharmacy - Shows how lipid nanocarriers are used in different types of treatment, including oral medicine, skin repair and cancer treatment - Assesses the pros and cons of using different lipid nanocarriers for different therapies

Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles

Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceutical systems, and the methods for their measurement. The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs. - Provides a clear description of the fundamentals of colloid and interface science relevant to drug research and development - Explains the physicochemical/colloidal basis of pharmaceutical science - Lists modern experimental characterization techniques, provides analytical equations and explanations on analyzing the experimental data - Describes the most advanced techniques, AFM (Atomic Force Microscopy), SFA (Surface Force Apparatus) in detail

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Colloidal carriers (particles, emulsions) for intravenous administration are a promising approach to achieve controlled release and site-specific delivery of drugs. The success of the systems will depend on their ability to maintain in blood circulation (controlled release system) or to reach target cells (e.g., bone marrow, blood cells). It is well known that the surface properties of i.v. injected particles are important factors determining the organ distribution and fate in vivo. Controlled surface modification could therefore be used to direct the carriers to the desired tissues. This book deals with the physico-chemical characterization of colloidal drug delivery systems and the influence of these parameters upon in vitro cell uptake and in vivo tissue distribution. Within the book, several different methods and their effect on surface characterization are discussed, and the in vivo tissue distribution of nanoparticles different in size and surface properties (coatings with Poloxamer/Polaximine/ethoxylated nonylphenols) and the carrier properties are examined in detail. The book does not deal with single aspects, but offers a comprehensive treatment of the subject. As a result, the book contributes to a better understanding of the factors influencing the organ distribution of i.v. drug carriers and provides useful information for the rational design of new carriers. It succeeds in clearing the way for future developments and the optimization of carriers for controlled drug delivery.