An examination of chirality as an environmental phenomenon

Chiral Organic Pollutants introduces readers to the growing challenges of chirality in synthetic chemicals. In this volume, contributors brilliantly summarize the characteristics of chiral pollutants to provide tools and techniques for effectively assessing their environmental and human health risks. Chapters cover recent research on the physicochemical properties, sources, exposure pathways, environmental fate, toxicity, and enantioselective analysis of chiral organic pollutants. Chiral Organic Pollutants also provides comprehensive discussions on the current trends in the synthesis and legislation of chiral chemicals. Key Features: Includes sampling and analytical methods for the enantioselective analysis of a wide array of chiral organic pollutants in food and the environment Summarizes recent research on the sources, fate, transport, and toxicity of chiral organic pollutants in the environment Critically examines the sources and pathways of chiral organic pollutants such as pesticides, pharmaceuticals, and flame retardants in food Includes a comprehensive discussion on current trends in the enantioselective synthesis and chiral switching of pesticides and pharmaceuticals Provides analysis of current national and international regulations of chiral synthetic chemicals The use of chiral synthetic chemicals such as pesticides, pharmaceuticals, personal care products, and halogenated flame retardants has significantly grown in the past 60 years. Hence, understanding the human and environmental health effects of chiral organic pollutants is crucial in the industry, academia, and policymaking. Chiral Organic Pollutants is an excellent textbook and reference for students, scientists, engineers, and policymakers interested in food quality, environmental pollution, chemical analysis, organic synthesis, and toxicology. Also available in the Food Analysis and Properties Series: Analysis of Nanoplastics and Microplastics in Food, edited by Leo. M.L. Nollet and Khwaja Salahuddin Siddiqi (ISBN: 9781138600188) Proteomics for Food Authentication, edited by Leo M.L. Nollet, and Semih Ötleş (ISBN: 9780367205058) Mass Spectrometry Imaging in Food Analysis, edited by Leo M.L. Nollet (ISBN: 9781138370692) For a complete list of books in this series, please visit our website at: www.crcpress.com/Food-Analysis--Properties/book-series/CRCFOODANPRO

Bisher gab es kein Buch, das sich speziell mit der Chiralität von Agrochemikalien beschäftigte, obwohl dieses Gebiet zunehmende Beachtung in der Industrie findet. Diese Darstellung der Chiralität bei Insektiziden, Fungiziden, Herbiziden und anderen Klassen von Agrochemikalien schließt diese Lücke. Synthese, Analytik, biologische Aktivität, Wirkprinzip, Toxikologie, Metabolismus und Umweltschicksal jeder besprochenen Verbindung werden diskutiert. (8/98)

This monograph contains a survey on the role of chirality in ecotoxicological processes. The focus is on environmental trace analysis. Areas such as toxicology, ecotoxicology, synthetic chemistry, biology, and physics are also covered in detail in order to explain the different properties of enantiomers in environmental samples. This monograph delivers a comprehensive survey for environmental trace analysts, analytical chemists, ecotoxicologists, food scientists and experienced lab workers.

Recently there has been growing concern about the hazards for man and his environment due to exposure to chemicals. One aspect receiving particular attention is that of the neglect of stereoselectivity in bioactive agents such as pesticides, drugs, etc. Mixtures of stereoisomers often contain 50 percent inactive material in the form of isomeric ballast. This ballast is pure environmental pollutant. Decisions as to whether the use of mixtures of stereoisomers is acceptable are only possible and acceptable if they are based on sound scientific information. It is the purpose of this volume to contribute to, and to disseminate, knowledge in this field. Written for workers in the field of pesticides, the book contains concise and basic information on stereoselectivity as a notable source of problems. Attention is paid to the involvement of stereoselectivity in important classes of pesticides as well as to pheromones and compounds derived from insect hormones with potential use in crop protection. Fundamentals of stereochemistry, stereoselective analytical methods, stereoselective synthesis and stereochemical aspects of the design of new compounds are also discussed.

Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.