Cerebrospinal Fluid (CSF) Proteomics
Title | Cerebrospinal Fluid (CSF) Proteomics PDF eBook |
Author | Enrique Santamaría |
Publisher | Humana |
Pages | 557 |
Release | 2019-08-21 |
Genre | Medical |
ISBN | 9781493997053 |
This volume focuses on protein analysis, including a wide range of the use of mass spectrometry and other protein methods within neurobiological disciplines. Chapters cover topics such as cerebrospinal fluid (CSF) processing and biobanking; label-free quantitative proteomics; SWATH; top-down proteomics; and experimental strategies based on other –omics applied to CSF metabolome, lipidome, and microRNAome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Cerebrospinal Fluid (CSF) Proteomics: Methods and Protocols is a valuable resource for graduate students and post-doctoral fellows interested in learning more about CSF proteotyping. It is also useful to established researchers seeking further insight into this growing field.
Cerebrospinal Fluid (CSF) Proteomics
Title | Cerebrospinal Fluid (CSF) Proteomics PDF eBook |
Author | Enrique Santamaría |
Publisher | Humana |
Pages | 557 |
Release | 2020-09-04 |
Genre | Medical |
ISBN | 9781493997084 |
This volume focuses on protein analysis, including a wide range of the use of mass spectrometry and other protein methods within neurobiological disciplines. Chapters cover topics such as cerebrospinal fluid (CSF) processing and biobanking; label-free quantitative proteomics; SWATH; top-down proteomics; and experimental strategies based on other –omics applied to CSF metabolome, lipidome, and microRNAome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Cerebrospinal Fluid (CSF) Proteomics: Methods and Protocols is a valuable resource for graduate students and post-doctoral fellows interested in learning more about CSF proteotyping. It is also useful to established researchers seeking further insight into this growing field.
The Neuronal Ceroid Lipofuscinoses (Batten Disease)
Title | The Neuronal Ceroid Lipofuscinoses (Batten Disease) PDF eBook |
Author | Sara Mole |
Publisher | OUP Oxford |
Pages | 480 |
Release | 2011-03-10 |
Genre | Medical |
ISBN | 019101558X |
The neuronal ceroid lipofuscinoses are an extremely rare group of inherited neurodegenerative diseases that primarily affect children. Core symptoms of these conditions typically include epilepsy, cognitive decline and visual failure. These diseases are so rare that professionals who come into contact with them need a consultative reference work that enables them to become expert, or identify who to contact for more details. Fully updated and revised, this second edition continues to be the definitive volume on this devastating group of disorders. Written by an international collection of authorities in the field, it provides invaluable advice on their diagnosis, patient care, and new treatments that are available. This new edition of the definitive reference text on the neuronal ceroid lipofuscinoses will prove useful for clinicians, family physicians, research scientists, diagnostic laboratories, families affected by the disease as well as by workers in industry planning translational research.
Cerebrospinal Fluid in Neurologic Disorders
Title | Cerebrospinal Fluid in Neurologic Disorders PDF eBook |
Author | |
Publisher | Elsevier |
Pages | 322 |
Release | 2017-11-17 |
Genre | Medical |
ISBN | 0128043245 |
Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. - Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker - Addresses relevant research in context with the most important diagnostic entities in neurology - Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available
Cerebrospinal Fluid in Clinical Neurology
Title | Cerebrospinal Fluid in Clinical Neurology PDF eBook |
Author | Florian Deisenhammer |
Publisher | Springer |
Pages | 442 |
Release | 2015-02-05 |
Genre | Medical |
ISBN | 3319012258 |
The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laboratory methods. By combining different CSF parameters, a wide range of diagnostic entities can be identified. However, properly interpreting the test results requires a high level of expertise and cannot be achieved by just reporting on individual analytic values. This book covers essential aspects of cerebrospinal fluid analysis and its use in the diagnosis of common neurological diseases. The first part addresses preclinical aspects such as the history of CSF, as well as the anatomical, physiological, and biological background of this valuable fluid. In addition, CSF collection, its preanalytical and methodological implications, and the increasing number of disease-specific markers in CSF are discussed in detail. Lastly, CSF analyses are put into context with clinical syndromes, demonstrating their diagnostic value in neurological clinical practice. Cerebrospinal Fluid in Clinical Neurology helps readers understand the preanalytical and analytical aspects of CSF diagnostics and offers a valuable reference guide for interpreting CSF results during the clinical work-up for neurological patients.
The Perioperative Neurocognitive Disorders
Title | The Perioperative Neurocognitive Disorders PDF eBook |
Author | Roderic G. Eckenhoff |
Publisher | Cambridge University Press |
Pages | 219 |
Release | 2019-03-28 |
Genre | Medical |
ISBN | 1107559200 |
A practical guide to perioperative cognitive disorders, the most common complications of anesthesia and surgery in older people.
Cerebrospinal Fluid Biomarkers
Title | Cerebrospinal Fluid Biomarkers PDF eBook |
Author | Charlotte E. Teunissen |
Publisher | Humana |
Pages | 236 |
Release | 2022-05-19 |
Genre | Medical |
ISBN | 9781071613214 |
This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.