This book addresses one of the most intriguing mysteries of our universe: the nature of dark matter. The results presented here mark a significant and substantial contribution to the search for new physics, in particular for new particles that couple to dark matter. The first analysis presented is a search for heavy new particles that decay into pairs of hadronic jets (dijets). This pioneering analysis explores unprecedented dijet invariant masses, reaching nearly 7 TeV, and sets constraints on several important new physics models. The two subsequent analyses focus on the difficult low dijet mass region, down to 200 GeV, and employ a novel technique to efficiently gather low-mass dijet events. The results of these analyses transcend the long-standing constraints on dark matter mediator particles set by several existing experiments.

Observations of neutrinos being emitted by the supernova SN1987A, star neutrinos, and atmospheric neutrinos have provided new insights into astronomy, as well as new unresolved phenomena such as the solar neutrino problem, spurring investigative studies among particle physicists and astrophysicists. One of the most important features of this book is its enumeration of a number of basic properties of neutrinos and their relationship to Grand Unified Theories, focusing on the origin of the neutrino's mass and the generation mixing of neutrinos. All the kamiokande results, detector performances, and complete references are included.

Surface Modification Technologies XIV presents the reviewed and edited proceedings of the SMT conference held September 2000, in Paris. The proceedings describe state-of-the-art surface engineering work in thermal spray, high-performance coatings, biomaterials, PVD, CVD, testing, wear resistance, laser-assisted surface modification, corrosion, and other topics. Contents include: Thermal spraying; High performance coatings; Bio materials; Testing and analysis; PVD and CVD; Wear; Laser processing; Corrosion and fatigue; Arts and surfaces; Plasma-assisted and advanced processes; Modeling; and Poster presentations.

An extensive body of evidence highlights the crucial importance of endocrine genetics. Examples range from human growth disorders and obesity to cancers of the prostate and breast. A pivotal part of the Modern Endocrinology Series, this book presents major biological studies underlining the significance of data obtained from knock-out mice, as well as from transgenic animals. Gene therapy and laboratory evaluation and screening of genetic endocrine diseases are covered, as are many of the classical endocrine diseases.

Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.